【标题速读】【Ncomm】【biological-sciences】【2022年】【7月】
声明：本专栏主要对生命科学领域的一些期刊文章标题进行翻译，所有内容均由本人手工整理翻译。由于本人专业为生物分析相关，其他领域如果出现翻译错误请谅解。
1.Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and infancy.
孕期和婴儿期mRNA疫苗产品和功能性抗体经胎盘转移的评估。
2.Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex.
IGF/IGFBP/ALS三元复合物的组装和拆卸的结构基础。
3.Maladaptive positive feedback production of ChREBPβ underlies glucotoxic β-cell failure.
ChREBPβ的不适应性正反馈生产是糖毒性β细胞衰竭的基础。
4.Knowledge-graph-based cell-cell communication inference for spatially resolved transcriptomic data with SpaTalk.
基于知识图谱的细胞-细胞通讯推断，用于空间分辨率的转录组数据与SpaTalk。
5.Structure-guided and phage-assisted evolution of a therapeutic anti-EGFR antibody to reverse acquired resistance.
结构指导和噬菌体辅助下的抗EGFR抗体的进化，以逆转获得性抗性。
6.RNA-binding protein RBM3 intrinsically suppresses lung innate lymphoid cell activation and inflammation partially through CysLT1R.
RNA结合蛋白RBM3部分通过CysLT1R内在地抑制了肺部先天淋巴细胞的激活和炎症。
7.Evidence accumulation occurs locally in the parietal cortex.
证据显示积累发生在顶叶皮层局部。
8.CDC-like kinase 4 deficiency contributes to pathological cardiac hypertrophy by modulating NEXN phosphorylation.
CDC样激酶4的缺失通过调节NEXN的磷酸化促进了病理性心脏肥大的发生。
9.Cholesterol sulfate alleviates ulcerative colitis by promoting cholesterol biosynthesis in colonic epithelial cells.
硫酸胆固醇通过促进结肠上皮细胞的胆固醇生物合成而缓解溃疡性结肠炎。
10.Balanced gene dosage control rather than parental origin underpins genomic imprinting.
平衡的基因剂量控制而不是父母的来源是基因组印记的基础。
11.Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling.
鸟苷酸结合蛋白对病原体的选择性杀伤是导致炎症体信号的分子机制。
12.Functional neuronal circuitry and oscillatory dynamics in human brain organoids.
人脑器官中的神经元功能回路和震荡动力学。
13.TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway.
TRIM28依赖的SUMOylation保护成年卵巢免受睾丸途径的激活。
14.SARS-CoV-2 VOC type and biological sex affect molnupiravir efficacy in severe COVID-19 dwarf hamster model.
SARS-CoV-2 VOC类型和生物性别影响莫尔纳比韦在严重COVID-19矮仓鼠模型中的疗效。
15.Neprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides.
尼普利酶通过裂解SERCA抑制性微肽调节肌肉收缩和心脏功能。
16.FLASHIda enables intelligent data acquisition for top–down proteomics to boost proteoform identification counts.
FLASHIda实现了自上而下蛋白质组学的智能数据采集，以提高蛋白质形态鉴定的数量。
17.Defunctionalizing intracellular organelles such as mitochondria and peroxisomes with engineered phospholipase A/acyltransferases.
用工程化的磷脂酶/脂肪转移酶使线粒体和过氧化物酶等细胞内细胞器去功能化。
18.Proteotoxicity caused by perturbed protein complexes underlies hybrid incompatibility in yeast.
由扰乱的蛋白质复合体引起的蛋白质毒性是酵母中杂交不相容的基础。
19.CDK9 activity switch associated with AFF1 and HEXIM1 controls differentiation initiation from epidermal progenitors.
与AFF1和HEXIM1相关的CDK9活性开关控制表皮祖细胞的分化启动。
20.Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade.
通过父母和胎儿免疫基因变异和细胞间通讯级联的小鼠胎儿生长受限。
21.Cross-validation of distance measurements in proteins by PELDOR/DEER and single-molecule FRET.
通过PELDOR/DEER和单分子FRET对蛋白质的距离测量进行交叉验证。
22.Cloning southern corn rust resistant gene RppK and its cognate gene AvrRppK from Puccinia polysora.
克隆南方玉米锈病抗性基因RppK及其来自Puccinia polysora的同源基因AvrRppK。
23.Gata6+ resident peritoneal macrophages promote the growth of liver metastasis.
Gata6+常驻腹腔巨噬细胞促进肝脏转移的生长。
24.Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration in mice.
转录因子网络分析确定REST/NRSF是小鼠中枢神经系统再生的内在调节因子。
25.An acquired phosphatidylinositol 4-phosphate transport initiates T-cell deterioration and leukemogenesis.
一种获得性磷脂酰肌醇-4-磷酸的运输启动了T细胞的恶化和白血病的发生。
26.Tryptophan C-mannosylation is critical for Plasmodium falciparum transmission.
色氨酸C-甘露糖基化对恶性疟原虫的传播至关重要。
27.Orbitofrontal cortex contributes to the comparison of values underlying economic choices.
眶额皮层有助于经济选择的基础价值比较。
28.Fatigue-free artificial ionic skin toughened by self-healable elastic nanomesh.
由自愈性弹性纳米网加固的无疲劳人工离子皮肤。
29.Cascaded dissipative DNAzyme-driven layered networks guide transient replication of coded-strands as gene models.
级联耗散DNA酶驱动的分层网络引导编码条带的瞬时复制作为基因模型。
a 由双链体 A/A' (0.2μM)、发夹 H1 (1μM) 和 Mg2+ 离子组成的反应模块的触发瞬态操作，产生 Mg2+ 离子依赖性脱氧核酶 T1/A。 b 瞬态浓度对应于：(i)-实线，在触发 T1 =⟩0.3⟩μM 的情况下，Mg2+-离子依赖性脱氧核酶 T1/A 的形成和消耗，以及 (i')-虚线，计算模拟 使用补充图 2 中提供的动力学模型的瞬态。瞬态和计算预测曲线 (ii)/(ii')，对应于在 T1 = 0.2⟩μM 存在下 T1 触发的 DNAzyme T1/A 形成/消耗，以及 (iii)/(iii') 瞬态和计算预测曲线，对应于在 T1 =⟩0.4⟩μM 存在下 DNAzyme T1/A 的形成/消耗。 插入：T1/A 在短时间间隔内随时间变化的动态演化：(i) 存在触发 T1 = 0.3 μM，(ii) 存在触发 T1 = 0.2⟩μM，(iii) 存在触发 T1 =⟩0.4 μM（对于瞬态的半衰期值，请参见补充图 6。）。 c a 中显示的瞬时 DNAzyme 循环 (T1 = 0.4 μM) 的循环操作。 箭头指示触发器 T1 的添加。
30.A multimodal iPSC platform for cystic fibrosis drug testing.
用于囊性纤维化药物测试的多模态iPSC平台。
31.HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis.
HSF1的磷酸化通过TRRAP-TIP60复合物建立活跃的染色质状态，并促进肿瘤的发生。
32.Dynamics of competing SARS-CoV-2 variants during the Omicron epidemic in England.
英国Omicron疫情期间竞争性SARS-CoV-2变体的动态变化。
33.Fire activity as measured by burned area reveals weak effects of ENSO in C.
由烧毁面积衡量的火灾活动揭示了C ENSO的微弱影响。
34.TidyMass an object-oriented reproducible analysis framework for LC–MS data.
TidyMass一个面向对象的LC-MS数据可重复分析框架。
35.Protein shape sampled by ion mobility mass spectrometry consistently improves protein structure prediction.
离子移动质谱采样的蛋白质形状持续改善蛋白质结构预测。
36.Reply to: Fire activity as measured by burned area reveals weak effects of ENSO in C.
Reply to： 以烧毁面积衡量的火灾活动揭示了C ENSO的微弱影响。
37.A unique class of Zn2+-binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile.
一类独特的Zn2+结合的丝氨酸基PBPs是艰难梭菌的头孢菌素抗性和孢子生成的基础。
38.Single-droplet surface-enhanced Raman scattering decodes the molecular determinants of liquid-liquid phase separation.
单滴表面增强拉曼散射破解了液-液相分离的分子决定因素。
39.A modular spring-loaded actuator for mechanical activation of membrane proteins.
用于机械激活膜蛋白的模块化弹簧推杆。
40.A density-based enrichment measure for assessing colocalization in single-molecule localization microscopy data.
用于评估单分子定位显微镜数据中的共聚焦的基于密度的富集措施。
41.Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes.
前列腺祖细胞中的雄性激素作用异常，通过IGF1和Wnt轴诱导致癌和肿瘤发展。
42.Fusion protein strategies for cryo-EM study of G protein-coupled receptors.
用于G蛋白偶联受体的低温电镜研究的融合蛋白策略。
43.Phosphatidylinositol-4-phosphate controls autophagosome formation in Arabidopsis thaliana.
磷脂酰肌醇-4-磷酸控制拟南芥中自噬体的形成。
44.De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
从自然发生的纳米晶体中重新确定杀蚊子的Cry11Aa和Cry11Ba结构。
45.PACAP-PAC1R modulates fear extinction via the ventromedial hypothalamus.
PACAP-PAC1R通过下丘脑外侧调控恐惧的消除。
46.Confinement anisotropy drives polar organization of two DNA molecules interacting in a nanoscale cavity.
封闭各向异性驱动两个DNA分子在纳米级腔体中相互作用的极性组织。
47.Sustainable environmental remediation via biomimetic multifunctional lignocellulosic nano-framework.
通过仿生多功能木质纤维素纳米框架的可持续环境修复。
48.Topological digestion drives time-varying rheology of entangled DNA fluids.
拓扑消化驱动纠缠的DNA流体的时间变化流变学。
49.Notch, RORC and IL-23 signals cooperate to promote multi-lineage human innate lymphoid cell differentiation.
Notch、RORC和IL-23信号合作促进多线人类先天淋巴细胞分化。
50.Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
Atm1的结构提供了关于[2F-2S]簇从线粒体输出的见解。
51.Dietary protein increases T-cell-independent sIgA production through changes in gut microbiota-derived extracellular vesicles.
膳食蛋白通过改变肠道微生物群衍生的胞外囊泡增加T细胞无关的sIgA产生。
52.Actin nano-architecture of phagocytic podosomes.
吞噬细胞荚膜的肌动蛋白纳米结构。
53.The Cryo-EM structures of two amphibian antimicrobial cross-β amyloid fibrils.
两种两栖动物抗菌性交叉β淀粉样纤维的低温电镜结构。
54.Targeting transcription in heart failure via CDK7/12/13 inhibition.
通过CDK7/12/13抑制针对心力衰竭的转录。
55.A live-attenuated SARS-CoV-2 vaccine candidate with accessory protein deletions.
一种具有附属蛋白缺失的SARS-CoV-2活体减毒疫苗候选者。
56.Body size, shape and ecology in tetrapods.
四足动物的体型、形状和生态学。
57.Genome-wide association study identifies Sjögren’s risk loci with functional implications in immune and glandular cells.
全基因组关联研究确定了具有免疫和腺体细胞功能影响的斯约克氏症风险位点。
58.Differential neutralization and inhibition of SARS-CoV-2 variants by antibodies elicited by COVID-19 mRNA vaccines.
COVID-19 mRNA疫苗激发的抗体对SARS-CoV-2变体的不同中和与抑制作用。
59.Decoding kinase-adverse event associations for small molecule kinase inhibitors.
解码小分子激酶抑制剂的激酶-不良事件关联。
60.Rare loss of function variants in the hepatokine gene INHBE protect from abdominal obesity.
肝素基因INHBE的罕见功能缺失变体对腹型肥胖的保护。
61.Cohesin couples transcriptional bursting probabilities of inducible enhancers and promoters.
Cohesin耦合了诱导性增强子和启动子的转录爆发概率。
62.Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn mice.
Triclosan的哺乳期传递促进了新生小鼠的非酒精性脂肪肝。
63.Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression.
全球ENIGMA研究中评估的局灶性和全身性癫痫的结构网络改变遵循癫痫风险基因表达的轴。
64.Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life.
母体和围产期肥胖通过IL-6-FoxO1轴诱导后天的支气管阻塞和肺部高血压。
65.ProtGPT2 is a deep unsupervised language model for protein design.
ProtGPT2是一个用于蛋白质设计的深度无监督语言模型。
66.UV photonic integrated circuits for far-field structured illumination autofluorescence microscopy.
用于远场结构化照明自发荧光显微镜的紫外光子集成电路.
67.Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila.
嗜肺军团菌HipBST毒素-抗毒素系统中毒素中和的分子机制。
68.Paeniclostridium sordellii hemorrhagic toxin targets TMPRSS2 to induce colonic epithelial lesions.
梭菌出血性毒素靶向TMPRSS2，诱发结肠上皮病变。
69.Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut.
人类肠道粘液酶对含O-聚糖斑块的糖蛋白的裂解的结构和机理的见解。
70.T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies.
T细胞受体β链靶向嵌合抗原受体T细胞对抗T细胞恶性肿瘤。
71.Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae.
霍乱弧菌的Na+泵送NADH-泛醌氧化还原酶的低温EM结构。
72.Global genomic analyses of wheat powdery mildew reveal association of pathogen spread with historical human migration and trade.
小麦白粉病的全球基因组分析揭示了病原体传播与历史上人类移民和贸易的关系。
73.Aggregative trans-eQTL analysis detects trait-specific target gene sets in whole blood.
聚合反式QTL分析检测全血中特异性状的目标基因集。
74.Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer.
靶向新生脂肪生成和Lands循环诱导KRAS突变型肺癌的铁中毒。
75.Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration.
老年性黄斑变性的转录组和蛋白质组特征。
76.An automated 13.5 hour system for scalable diagnosis and acute management guidance for genetic diseases.
用于遗传性疾病的可扩展诊断和急性管理指导的13.5小时自动化系统。
77.Win-win opportunities combining high yields with high multi-taxa biodiversity in tropical agroforestry.
热带农林业中高产量与高多塔生物多样性相结合的双赢机会。
78.Plastic pollution fosters more microbial growth in lakes than natural organic matter.
塑料污染比天然有机物更能促进湖泊中的微生物生长。
79.Engineered bioorthogonal POLY-PROTAC nanoparticles for tumour-specific protein degradation and precise cancer therapy.
用于肿瘤特异性蛋白质降解和精确癌症治疗的工程化生物正交POLY-PROTAC纳米粒子。
80.Phenylalanine impairs insulin signaling and inhibits glucose uptake through modification of IRβ.
苯丙氨酸通过修饰IRβ损害胰岛素信号并抑制葡萄糖摄取。
81.KSTAR: An algorithm to predict patient-specific kinase activities from phosphoproteomic data.
KSTAR：一种从磷蛋白组数据中预测患者特定激酶活性的算法。
82.Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC.
保留淋巴的治疗顺序与免疫检查点的抑制释放了HNSCC的CDC1依赖性抗肿瘤免疫力。
83.Postmitotic differentiation of human monocytes requires cohesin-structured chromatin.
人类单核细胞的有丝分裂后的分化需要粘连蛋白结构的染色质。
84.Cell landscape of larval and adult Xenopus laevis at single-cell resolution.
单细胞分辨率下的幼虫和成虫的细胞景观。
85.Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain.
HMG CoA还原酶的调节性降解需要甾醇感应结构域的构象变化。
86.Light-activated mitochondrial fission through optogenetic control of mitochondria-lysosome contacts.
通过光遗传学控制线粒体-lysosome接触的光激活线粒体裂变。
87.Structure and assembly of cargo Rubisco in two native α-carboxysomes.
两个本地α-羧基体中货物Rubisco的结构和组装。
88.Extreme purifying selection against point mutations in the human genome.
人类基因组中针对点突变的极端纯化选择。
89.Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo.
母体SMCHD1调控小鼠胚胎中Hox基因的表达和模式化.
90.The architecture of kinesin-3 KLP-6 reveals a multilevel-lockdown mechanism for autoinhibition.
kinesin-3 KLP-6的结构揭示了一种多级锁定的自我抑制机制.
91.Frequency spectra and the color of cellular noise.
频谱和细胞噪声的颜色。
92.Length-dependent motions of SARS-CoV-2 frameshifting RNA pseudoknot and alternative conformations suggest avenues for frameshifting suppression.
SARS-CoV-2移帧RNA假结的长度依赖性运动和替代构象表明移帧抑制的途径。
93.Noise correlations in neural ensemble activity limit the accuracy of hippocampal spatial representations.
神经集合活动中的噪声相关性限制了海马空间表征的准确性。
94.Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
ATR在肺泡横纹肌肉瘤中的治疗目标。
95.The RalGAPα1–RalA signal module protects cardiac function through regulating calcium homeostasis.
RalGAPα1-RalA信号模块通过调节钙平衡保护心脏功能。
96.Single-cell transcriptome atlas of the human corpus cavernosum.
人类海绵体的单细胞转录组图谱。
97.Multi-step screening of DNA/lipid nanoparticles and co-delivery with siRNA to enhance and prolong gene expression.
多步骤筛选DNA/脂质纳米颗粒并与siRNA共同传递以增强和延长基因表达。
98.Structural basis of human TREX1 DNA degradation and autoimmune disease.
人类TREX1 DNA降解和自身免疫性疾病的结构基础。
99.An analysis of 45 large-scale wastewater sites in England to estimate SARS-CoV-2 community prevalence.
对英格兰45个大规模废水点的分析，以估计SARS-CoV-2的社区流行率。
100.Warming and redistribution of nitrogen inputs drive an increase in terrestrial nitrous oxide emission factor.
气候变暖和氮素输入的重新分布推动了陆地氧化亚氮排放因子的增加。
101.Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis.
ERG信号传导功能失调驱动肺血管老化和持续纤维化。
102.Pancreatic tumor eradication via selective Pin1 inhibition in cancer-associated fibroblasts and T lymphocytes engagement.
通过选择性抑制癌症相关成纤维细胞和T淋巴细胞的Pin1根除胰腺肿瘤的作用。
103.DNA nicks induce mutational signatures associated with BRCA1 deficiency.
DNA钉子诱发与BRCA1缺陷相关的突变特征。
104.Integrin α3β1 promotes vessel formation of glioblastoma-associated endothelial cells through calcium-mediated macropinocytosis and lysosomal exocytosis.
整合素α3β1通过钙介导的巨噬细胞和溶酶体外渗作用促进胶质母细胞相关内皮细胞的血管形成。
105.A phylogenetically-restricted essential cell cycle progression factor in the human pathogen Candida albicans.
人类病原体白色念珠菌中一个系统发育受限的基本细胞周期进展因子。
106.Discovering the drivers of clonal hematopoiesis.
发现克隆性造血的驱动因素。
107.Extensive co-binding and rapid redistribution of NANOG and GATA6 during emergence of divergent lineages.
NANOG和GATA6在分歧系出现过程中的广泛共同结合和快速重新分布。
108.Development of a nanoparticle-based immunotherapy targeting PD-L1 and PLK1 for lung cancer treatment.
基于纳米颗粒的免疫疗法的发展，以PD-L1和PLK1为目标，用于肺癌治疗。
109.Natural variation of DROT1 confers drought adaptation in upland rice.
DROT1的自然变异赋予高地水稻的干旱适应性。
110.A proteolytically activated antimicrobial toxin encoded on a mobile plasmid of Bacteroidales induces a protective response.
菌类的移动质粒上编码的蛋白溶解活性抗菌毒素诱导保护性反应。
111.Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector.
Rep15与几个Rab GTP酶相互作用，并具有Rab效应器的独特折叠。
112.Landscape of somatic alterations in large-scale solid tumors from an Asian population.
来自亚洲人群的大规模实体肿瘤中体细胞改变的景观。
113.Multiple anthropogenic pressures eliminate the effects of soil microbial diversity on ecosystem functions in experimental microcosms.
多种人为压力消除了实验性微生态环境中土壤微生物多样性对生态系统功能的影响。
114.Construction of the axolotl cell landscape using combinatorial hybridization sequencing at single-cell resolution.
利用组合杂交测序在单细胞分辨率下构建斧头鱼的细胞景观。
115.A multi-omic dissection of super-enhancer driven oncogenic gene expression programs in ovarian cancer.
卵巢癌中超级增强子驱动的致癌基因表达程序的多组学剖析。
116.Heparin induces α-synuclein to form new fibril polymorphs with attenuated neuropathology.
肝素诱导α-synuclein形成新的纤维多态性，减轻神经病理学的影响。
117.Modulating co-translational protein folding by rational design and ribosome engineering.
通过合理设计和核糖体工程调控共翻译蛋白折叠。
118.Accurate somatic variant detection using weakly supervised deep learning.
使用弱监督的深度学习进行准确的体细胞变异检测。
119.Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymoma.
胸腺瘤中髓质胸腺上皮细胞异常神经肌肉基因的表达。
120.Calcium/calmodulin-dependent protein kinase IV promotes imiquimod-induced psoriatic inflammation via macrophages and keratinocytes in mice.
钙/钙调蛋白依赖性蛋白激酶IV通过小鼠的巨噬细胞和角质细胞促进咪喹莫特诱导的银屑病炎症。
121.Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations.
DNMT3B同源多聚体的结构显示出易受ICF突变的损害。
122.A temperature-regulated circuit for feeding behavior.
摄食行为的温度调节回路。
123.Targeting loop3 of sclerostin preserves its cardiovascular protective action and promotes bone formation.
靶向sclerostin的loop3可保留其心血管保护作用并促进骨形成。
124.Development of a novel core genome MLST scheme for tracing multidrug resistant Staphylococcus capitis.
用于追踪多药耐药葡萄球菌的新型核心基因组MLST方案的开发。
125.Predicting memory from the network structure of naturalistic events.
从自然事件的网络结构中预测记忆。
126.Personalized bacteriophage therapy to treat pandrug-resistant spinal Pseudomonas aeruginosa infection.
个性化的噬菌体疗法治疗耐药性脊柱铜绿假单胞菌感染。
127.A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells.
机械传感器PIEZO1在葡萄糖诱导的胰岛素分泌中的关键作用。
128.Neurocomputational mechanisms of confidence in self and others.
对自己和他人的信心的神经计算机制。
129.Nanoscale regulation of Ca2+ dependent phase transitions and real-time dynamics of SAP97/hDLG.
Ca2+依赖性相变的纳米级调节和SAP97/hDLG的实时动态。
130.TDP1-independent pathways in the process and repair of TOP1-induced DNA damage.
TOP1诱导的DNA损伤的过程和修复中不依赖TDP1的途径。
131.Differential analysis of RNA structure probing experiments at nucleotide resolution: uncovering regulatory functions of RNA structure.
核苷酸分辨率下的RNA结构探测实验的差异分析：揭示RNA结构的调控功能。
132.A macroscopic link between interhemispheric tract myelination and cortico-cortical interactions during action reprogramming.
行动重编程过程中半球间束髓化和皮质-皮质相互作用之间的宏观联系。
133.Altered tRNA dynamics during translocation on slippery mRNA as determinant of spontaneous ribosome frameshifting.
滑溜溜的mRNA上易位时改变的tRNA动态是自发核糖体移架的决定因素。
134.Emergency triage of brain computed tomography via anomaly detection with a deep generative model.
通过深度生成模型的异常检测对大脑计算机断层成像进行紧急分流。
135.Detection of neutralizing antibodies against multiple SARS-CoV-2 strains in dried blood spots using cell-free PCR.
利用无细胞PCR检测干血斑中针对多种SARS-CoV-2毒株的中和抗体.
136.Etv2 regulates enhancer chromatin status to initiate Shh expression in the limb bud.
Etv2调控增强子染色质状态以启动肢芽中的Shh表达。
137.Population genomics of Group B Streptococcus reveals the genetics of neonatal disease onset and meningeal invasion.
B组链球菌的群体基因组学揭示了新生儿疾病发病和脑膜侵入的遗传学。
138.Water as the often neglected medium at the interface between materials and biology.
水是材料和生物学界面上经常被忽视的介质。
139.Post-translational amino acid conversion in photosystem II as a possible origin of photosynthetic oxygen evolution.
光系统II的翻译后氨基酸转换是光合氧进化的可能起源。
140.Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex.
异质核糖核酸蛋白U（HNRNPU）保障了发育中的小鼠皮层。
141.Biallelic and gene-wide genomic substitution for endogenous intron and retroelement mutagenesis in human cells.
人类细胞中内源性内含子和逆转录元素突变的双片和全基因组替代。
142.Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice.
投射到背脊核的外侧哈维纳谷氨酸神经元促进小鼠的攻击性唤醒。
143.Engineered biomimetic nanoparticles achieve targeted delivery and efficient metabolism-based synergistic therapy against glioblastoma.
工程化仿生纳米粒子实现了对胶质母细胞瘤的靶向输送和基于代谢的高效协同治疗。
144.Dynamic influences on static measures of metacognition.
对元认知的静态措施的动态影响。
145.A metagenomic DNA sequencing assay that is robust against environmental DNA contamination.
一种对环境DNA污染具有鲁棒性的元基因组DNA测序方法。
146.Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration.
靶向视黄酸受体α-核抑制器的相互作用激活伴侣素介导的自噬并保护视网膜变性。
147.A nationwide questionnaire study of post-acute symptoms and health problems after SARS-CoV-2 infection in Denmark.
丹麦SARS-CoV-2感染后急性症状和健康问题的全国性问卷研究。
148.Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin.
Tc毒素对F-actin的苏氨酸ADP-核苷酸化的机制。
149.A Bayesian approach to infer recombination patterns in coronaviruses.
用贝叶斯方法推断冠状病毒的重组模式.
150.Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape.
Kinesin-8特异性环路-2根据管蛋白原丝形状控制运动域的双重活动.
151.Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding.
铜绿假单胞菌SutA楔入RNAP叶状结构域以促进启动子DNA解开。
152.Model-guided engineering of DNA sequences with predictable site-specific recombination rates.
模型指导下的DNA序列工程，具有可预测的特定位点重组率。
153.An epigenome atlas of neural progenitors within the embryonic mouse forebrain.
胚胎期小鼠前脑内神经祖先的表观基因组图谱。
154.Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability.
Neuropilin 1及其抑制性配体mini-tryptophanyl-tRNA synthetase反向调节VE-cadherin周转和血管通透性。
155.Drivers and trends of global soil microbial carbon over two decades.
二十年来全球土壤微生物碳的驱动力和趋势.
156.Polycomb-lamina antagonism partitions heterochromatin at the nuclear periphery.
Polycomb-lamina的拮抗作用将异染色质分割在核周边。
157.Disruption of tubulin-alpha4a polyglutamylation prevents aggregation of hyper-phosphorylated tau and microglia activation in mice.
破坏管蛋白-α4a的聚谷氨酸化可防止小鼠高磷酸化tau的聚集和小胶质细胞的激活。
158.Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophin expression.
Sirt6的失活通过释放对utrophin表达的抑制改善了mdx小鼠的肌肉萎缩。
159.Thalamo-hippocampal pathway regulates incidental memory capacity in mice.
Thalamo-hippocampal通路调节小鼠的附带记忆能力。
160.The mechanism of replication stalling and recovery within repetitive DNA.
重复性DNA内复制停顿和恢复的机制。
161.Stomatin modulates adipogenesis through the ERK pathway and regulates fatty acid uptake and lipid droplet growth.
Stomatin通过ERK途径调节脂肪生成，并调节脂肪酸的摄取和脂滴的生长。
162.Genomic insights into the secondary aquatic transition of penguins.
对企鹅二级水生过渡的基因组学见解。
163.α-Synuclein fibril-specific nanobody reduces prion-like α-synuclein spreading in mice.
α-Synuclein纤维特异性纳米抗体减少小鼠中类似朊病毒的α-synuclein扩散。
164.A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours.
大脑前体图谱揭示了成人脑肿瘤中类似发育状态的获得。
165.Increased neutralization and IgG epitope identification after MVA-MERS-S booster vaccination against Middle East respiratory syndrome.
针对中东呼吸综合征的MVA-MERS-S加强型疫苗接种后，中和作用和IgG表位鉴定增加。
166.Drought-Induced Civil Conflict Among the Ancient Maya.
古代玛雅人中干旱引起的内部冲突.
167.Reactivity-dependent profiling of RNA 5-methylcytidine dioxygenases.
RNA 5-甲基胞苷二氧化酶的反应性依赖分析。
168.N6-methyladenosine modification-mediated mRNA metabolism is essential for human pancreatic lineage specification and islet organogenesis.
N6-甲基腺苷修饰介导的mRNA代谢对人类胰腺线型规范和胰岛器官生成至关重要。
169.Periosteal stem cells control growth plate stem cells during postnatal skeletal growth.
骨膜干细胞在产后骨骼生长过程中控制生长板干细胞。
170.Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression.
腺苷A1受体激动剂对Gαob的选择性激活引起镇痛而无心肺功能抑制。
171.Duration of protection of CoronaVac plus heterologous BNT162b2 booster in the Omicron period in Brazil.
巴西Omicron时期CoronaVac加异源BNT162b2助推器的保护时间。
172.Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults.
接种疫苗的成年人在Omicron SARS-CoV-2突破性感染中的免疫反应。
173.People infer communicative action through an expectation for efficient communication.
人们通过对高效沟通的期望来推断沟通行动。
174.Structural basis for the activation and ligand recognition of the human oxytocin receptor.
人类催产素受体的激活和配体识别的结构基础。
175.Orexin neurons inhibit sleep to promote arousal.
Orexin神经元抑制睡眠以促进唤醒。
176.Proteomic analysis reveals key differences between squamous cell carcinomas and adenocarcinomas across multiple tissues.
蛋白质组学分析揭示了鳞状细胞癌和腺癌在多种组织中的关键差异。
177.Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells.
来自衰老细胞的肝细胞生长因子减弱了细胞竞争引起的致癌细胞的顶端消除。
178.Age-dependent changes in circulating Tfh cells influence development of functional malaria antibodies in children.
循环Tfh细胞的年龄依赖性变化影响儿童功能性疟疾抗体的发展。
179.Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications.
利用近红外可激活蛋白结合的纳米粒子进行高效的空间定向基因编辑，用于脑部应用。
180.ZnT8 loss-of-function accelerates functional maturation of hESC-derived β cells and resists metabolic stress in diabetes.
ZnT8功能缺失加速了hESC衍生的β细胞的功能成熟并抵抗糖尿病的代谢压力。
181.The CIP2A-TOPBP1 complex safeguards chromosomal stability during mitosis.
CIP2A-TOPBP1复合物在有丝分裂过程中保障了染色体的稳定性。
182.Lysosomal protein transmembrane 5 promotes lung-specific metastasis by regulating BMPR1A lysosomal degradation.
溶酶体蛋白跨膜5通过调节BMPR1A溶酶体降解促进肺部特定转移。
183.Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance.
激活VCP D1 ATP酶的化合物同时增强了自噬和蛋白体神经毒性蛋白的清除。
184.Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity.
免疫相关GTP酶GM4951的缺失导致非酒精性脂肪肝而无肥胖症。
185.Timing is everything: structural insights into the disease-linked Kv3 channels controlling fast action-potential firing in the brain.
时间就是一切：对控制大脑快速动作电位发射的与疾病相关的Kv3通道的结构见解。
186.MRTF specifies a muscle-like contractile module in Porifera.
MRTF在多孔类动物中指定了一个类似肌肉的收缩模块。
187.A synaptic signal for novelty processing in the hippocampus.
海马体中新奇事物处理的突触信号。
188.The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance.
多发性骨髓瘤细胞的表面组提示潜在的免疫治疗策略和耐药性的蛋白质标记。
189.Somatic cell fate maintenance in mouse fetal testes via autocrine/paracrine action of AMH and activin B.
通过AMH和激活素B的自分泌/旁分泌作用维持小鼠胎儿睾丸中的体细胞命运。
190.Cutaneous and acral melanoma cross-OMICs reveals prognostic cancer drivers associated with pathobiology and ultraviolet exposure.
皮肤和尖锐黑色素瘤交叉OMIC揭示了与病理生物学和紫外线暴露有关的预后癌症驱动因素。
191.Recovery of Lutacidiplasmatales archaeal order genomes suggests convergent evolution in Thermoplasmatota.
恢复Lutacidiplasmatales古生物秩序基因组表明Thermoplasmatota的趋同进化。
192.Oncogenic BRAF induces whole-genome doubling through suppression of cytokinesis.
肿瘤性BRAF通过抑制细胞分裂诱导全基因组加倍。
193.Inhibition of NMDA receptors through a membrane-to-channel path.
通过膜到通道的途径抑制NMDA受体。
194.Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain.
人类Kv3.1通道的冷冻电镜结构显示了细胞质T1结构域的门控。
195.Hepatic non-parenchymal S100A9-TLR4-mTORC1 axis normalizes diabetic ketogenesis.
肝脏非血小板S100A9-TLR4-mTORC1轴使糖尿病生酮作用正常化。
196.SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function and cognition in mice.
与神经发育障碍相关的SLITRK2变体损害了小鼠的兴奋性突触功能和认知能力。
197.Hypoxia induces HIF1α-dependent epigenetic vulnerability in triple negative breast cancer to confer immune effector dysfunction and resistance to anti-PD-1 immunotherapy.
低氧诱导三阴性乳腺癌的HIF1α依赖性表观遗传脆弱性，赋予免疫效应器功能障碍和对抗PD-1免疫疗法的抗性。
198.Trigger factor both holds and folds its client proteins.
触发因子既保持又折叠其客户蛋白。
199.Building programmable multicompartment artificial cells incorporating remotely activated protein channels using microfluidics and acoustic levitation.
利用微流控技术和声学悬浮技术建立可编程的多室人工细胞，其中包括远程激活的蛋白质通道。
200.Humanized mice for investigating sustained Plasmodium vivax blood-stage infections and transmission.
用于研究持续间日疟血液阶段感染和传播的人性化小鼠。
201.Differences in barriers for controlled learning about safety between biotechnology and chemistry.
生物技术和化学之间的安全控制学习障碍的差异。
202.Identifying multicellular spatiotemporal organization of cells with SpaceFlow.
用SpaceFlow识别细胞的多细胞时空组织。
203.Cell-autonomous Hedgehog signaling controls Th17 polarization and pathogenicity.
细胞自主的Hedgehog信号控制Th17的极化和致病性。
204.Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity.
自然杀伤细胞表现出独特的eQTL和全转录组疾病关联，突出了其在自身免疫中的作用。
205.A monomeric mycobacteriophage immunity repressor utilizes two domains to recognize an asymmetric DNA sequence.
一个单体的噬菌体免疫抑制器利用两个结构域来识别不对称的DNA序列。
206.HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8+ T-cell infiltration into tumors.
HRS磷酸化驱动免疫抑制性外泌体的分泌，并限制CD8+T细胞对肿瘤的浸润。
207.Inhibition of myeloid-derived suppressor cell arginase-1 production enhances T-cell-based immunotherapy against Cryptococcus neoformans infection.
抑制骨髓源性抑制细胞精氨酸酶-1的产生增强了基于T细胞的免疫疗法对抗新隐球菌感染。
208.Breaking photoswitch activation depth limit using ionising radiation stimuli adapted to clinical application.
利用适应临床应用的电离辐射刺激打破光开关的激活深度限制。
209.A time-resolved multi-omics atlas of Acanthamoeba castellanii encystment.
蓖麻杆菌囊肿的时间分辨多组学图谱.
210.Structures of β1-adrenergic receptor in complex with Gs and ligands of different efficacies.
β1-肾上腺素能受体与Gs和不同功效配体的复合体结构.
211.Auxotrophic and prototrophic conditional genetic networks reveal the rewiring of transcription factors in Escherichia coli.
辅助型和原型型条件遗传网络揭示了大肠杆菌中转录因子的重构。
212.Microglia coordinate cellular interactions during spinal cord repair in mice.
小胶质细胞协调小鼠脊髓修复过程中的细胞相互作用。
213.Controlled activation of cortical astrocytes modulates neuropathic pain-like behaviour.
皮质星形胶质细胞的控制性激活可调节神经性疼痛样行为。
214.Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension.
加速赖氨酸代谢传达盐敏感性高血压的肾脏保护。
215.Equilibrated evolution of the mixed auto-/allopolyploid haplotype-resolved genome of the invasive hexaploid Prussian carp.
侵入性六倍体普鲁士鲤鱼的混合自体/全多倍体单倍型解析基因组的平衡进化。
216.Adipocyte lysoplasmalogenase TMEM86A regulates plasmalogen homeostasis and protein kinase A-dependent energy metabolism.
脂肪细胞溶血素酶TMEM86A调控溶血素平衡和蛋白激酶A依赖的能量代谢。
217.Phagocytosis of Plasmodium falciparum ring-stage parasites predicts protection against malaria.
恶性疟原虫环状阶段寄生虫的吞噬作用预测了对疟疾的保护。
218.The shape of things to come: structural insights into how prion proteins encipher heritable information.
未来事物的形态：对朊病毒蛋白如何加密遗传信息的结构见解。
219.Cryo-EM structure of anchorless RML prion reveals variations in shared motifs between distinct strains.
无锚的RML朊病毒的低温电镜结构揭示了不同菌株之间共享图案的变化。
220.The intrinsically disordered protein TgIST from Toxoplasma gondii inhibits STAT1 signaling by blocking cofactor recruitment.
弓形虫的内在无序蛋白TgIST通过阻断辅助因子的招募来抑制STAT1的信号传导。
221.2.7 Å cryo-EM structure of ex vivo RML prion fibrils.
体外RML朊病毒纤维的2.7埃低温电镜结构。
222.Bromodomain factor 5 is an essential regulator of transcription in Leishmania.
溴域因子5是利什曼病毒转录的一个重要调节器。
223.A reference single-cell regulomic and transcriptomic map of cynomolgus monkeys.
犬牙交错的单细胞调控和转录组参考图。
224.Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
用于加速蛋白质相互作用组发现的可扩展的多重联合分馏/质谱分析平台。
225.Integration of tumor extrinsic and intrinsic features associates with immunotherapy response in non-small cell lung cancer.
肿瘤外在和内在特征的整合与非小细胞肺癌的免疫治疗反应有关。
226.Model building of protein complexes from intermediate-resolution cryo-EM maps with deep learning-guided automatic assembly.
利用深度学习引导的自动装配，从中分辨率低温电镜图中建立蛋白质复合体模型。
227.Massively targeted evaluation of therapeutic CRISPR off-targets in cells.
细胞中治疗性CRISPR脱靶的大规模定向评估。
228.De-etiolation-induced protein 1 (DEIP1) mediates assembly of the cytochrome b6f complex in Arabidopsis.
脱叶诱导蛋白1（DEIP1）介导了拟南芥中细胞色素b6f复合物的组装。
229.A SOX17-PDGFB signaling axis regulates aortic root development.
SOX17-PDGFB信号轴调控主动脉根的发育。
230.Monomeric prefusion structure of an extremophile gamete fusogen and stepwise formation of the postfusion trimeric state.
一个极端亲缘配子体融合前的单体结构和融合后三聚体状态的逐步形成。
231.Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.
与疾病相关的MEK突变体的质量差异揭示了癌症的分子特征和异常信号传导-串扰。
232.Single cell sequencing identifies clonally expanded synovial CD4+ TPH cells expressing GPR56 in rheumatoid arthritis.
单细胞测序确定了类风湿关节炎中表达GPR56的滑膜CD4+TPH细胞的克隆扩展。
233.Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions.
人型唾液酸受体通过异质多价的相互作用对禽类甲型流感病毒的结合和进入做出贡献。
234.Selective expression of variant surface antigens enables Plasmodium falciparum to evade immune clearance in vivo.
变体表面抗原的选择性表达使恶性疟原虫在体内逃避免疫清除。
235.The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors.
HHIP-AS1 lncRNA通过稳定人类SHH驱动的肿瘤中的dynein complex 1来促进肿瘤的发生。
236.Community voices: policy proposals to promote inclusion in academia through the lens of women in science.
社区的声音：通过科学界女性的视角促进学术界的包容性的政策建议。
237.Loop-extrusion and polymer phase-separation can co-exist at the single-molecule level to shape chromatin folding.
Loop-extrusion和聚合物相分离可以在单分子水平上共存以塑造染色质的折叠。
238.CD8 lymphocytes mitigate HIV-1 persistence in lymph node follicular helper T cells during hyperacute-treated infection.
CD8淋巴细胞缓解了超急性感染期间HIV-1在淋巴结滤泡辅助T细胞中的持续存在。
239.Deciphering polymorphism in 61,157 Escherichia coli genomes via epistatic sequence landscapes.
通过外显序列景观破译61157个大肠杆菌基因组的多态性。
240.Genome-wide signatures of synergistic epistasis during parallel adaptation in a Baltic Sea copepod.
波罗的海桡足动物平行适应过程中的全基因组协同外显性特征。
241.Ultra-sensitive monitoring of leukemia patients using superRCA mutation detection assays.
使用superRCA突变检测法对白血病患者进行超灵敏的监测。
通过 PCR 扩增样品中感兴趣的 DNA 序列。 B 扩增的链通过其 5' 和 3' 末端的模板化连接转化为单链 DNA 环。 C 模板化环化反应的寡核苷酸接下来用作 RCA 反应的引物。 D 然后用突变体或野生型序列特异的挂锁探针检测 RCA 产物。 E 连接的挂锁探针，缠绕在 RCA 产物周围，然后模板二级 RCA 反应，由添加的寡核苷酸引发。 F 对于每个起始 DNA 环，反应会产生主要为单链 DNA 对象的大簇，称为 superRCA 产物。 多达一百万个荧光标记的杂交探针可以结合每个突变体或野生型特异性产物，从而允许通过例如标准流式细胞术进行有效计数。
242.Genomic epidemiology of Delta SARS-CoV-2 during transition from elimination to suppression in Aotearoa New Zealand.
新西兰Aotearoa地区SARS-CoV-2病毒从消除到抑制过渡期间的基因组流行病学。
243.An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides.
一种LNA-酰胺修饰，增强了细胞对硫代磷酸酯外显子跳过寡核苷酸的吸收和活性。
244.Precision cancer sono-immunotherapy using deep-tissue activatable semiconducting polymer immunomodulatory nanoparticles.
利用深层组织可激活的半导体聚合物免疫调节纳米颗粒进行精确的癌症声学免疫治疗。
245.Malaria parasite heme biosynthesis promotes and griseofulvin protects against cerebral malaria in mice.
疟原虫血红素生物合成对小鼠脑性疟疾的促进和格列本脲的保护作用。
246.Base editing in human cells with monomeric DddA-TALE fusion deaminases.
单体DddA-TALE融合脱氨酶在人类细胞中的碱基编辑。
247.A randomized phase 3 trial of Gemcitabine or Nab-paclitaxel combined with cisPlatin as first-line treatment in patients with metastatic triple-negative breast cancer.
吉西他滨或纳布-紫杉醇联合顺铂作为转移性三阴性乳腺癌患者的一线治疗的随机3期试验。
248.Trypsin is a coordinate regulator of N and P nutrients in marine phytoplankton.
胰蛋白酶是海洋浮游植物中N和P营养成分的协调调节剂。
249.Self-assembly of tessellated tissue sheets by expansion and collision.
通过扩张和碰撞实现方块组织片的自组装。
a-d 相同大小的矩形 (a)、相同大小的圆 (b)、大小不匹配的圆 (c) 和圆-矩形对 (d) 的原型碰撞实验（实线）和模拟（轮廓线）。 最右边的图中显示了 60 h 时几个组织的平均值 (n = 4–7)。
250.Cumulative cultural evolution and mechanisms for cultural selection in wild bird songs.
野生鸟类歌曲的累积性文化演化和文化选择机制.
251.Single-cell analysis highlights differences in druggable pathways underlying adaptive or fibrotic kidney regeneration.
单细胞分析突出了适应性或纤维化肾脏再生的可药性途径的差异。
252.Nestin-dependent mitochondria-ER contacts define stem Leydig cell differentiation to attenuate male reproductive ageing.
Nestin依赖的线粒体-ER接触定义了干系的Leydig细胞分化以减弱男性生殖衰老。
253.Spatially resolved proteomic map shows that extracellular matrix regulates epidermal growth.
空间分辨率的蛋白质组图显示细胞外基质调控表皮生长。
254.Reply to: Questioning whether the IgM Fc receptor (FcμR) is expressed by innate immune cells.
回复：： 质疑IgM Fc受体（FcμR）是否由先天免疫细胞表达。
255.Questioning whether IgM Fc receptor (FcµR) is expressed by innate immune cells.
质疑IgM Fc受体(FcμR)是否由先天免疫细胞表达。
256.Translational fidelity and growth of Arabidopsis require stress-sensitive diphthamide biosynthesis.
拟南芥的翻译保真度和生长需要对压力敏感的双硫脒生物合成。
257.Machine learning-based tissue of origin classification for cancer of unknown primary diagnostics using genome-wide mutation features.
基于机器学习的原发组织分类，利用全基因组突变特征对未知原发癌症进行诊断。
258.Blocking glycine utilization inhibits multiple myeloma progression by disrupting glutathione balance.
阻断甘氨酸利用通过破坏谷胱甘肽平衡抑制多发性骨髓瘤的进展。
259.Regulation of AUXIN RESPONSE FACTOR condensation and nucleo-cytoplasmic partitioning.
AUXIN RESPONSE FACTOR凝结和核-质体分配的调节。
260.Chromatin sequesters pioneer transcription factor Sox2 from exerting force on DNA.
染色质封存先锋转录因子Sox2，使其无法对DNA施力。
261.Compulsive alcohol drinking in rodents is associated with altered representations of behavioral control and seeking in dorsal medial prefrontal cortex.
啮齿动物的强迫性饮酒与背内侧前额叶皮层的行为控制和寻求的表征改变有关。
262.Interchromosomal interaction of homologous Stat92E alleles regulates transcriptional switch during stem-cell differentiation.
同源的Stat92E等位基因的染色体间相互作用调节了干细胞分化过程中的转录转换。
263.Precision digital mapping of endogenous and induced genomic DNA breaks by INDUCE-seq.
INDUCE-seq对内源性和诱导性基因组DNA断裂的精确数字图谱。
264.Programmable CRISPR-Cas9 microneedle patch for long-term capture and real-time monitoring of universal cell-free DNA.
可编程CRISPR-Cas9微针贴片用于长期捕获和实时监测通用无细胞DNA。
a 可穿戴贴片制造的工作流程。 b 显示 CRISPR 微针与 dCas9 酶和固定在羧基石墨烯表面上的序列特异性 sgRNA（表示为 dRNP）集成的方案。 c 基于反向离子电渗疗法和 CRISPR-Cas9 激活的石墨烯生物界面实时监测富集的 cfDNA。 cfDNA对dRNP的特异性识别调节石墨烯层的电化学特性和电位差，产生电信号输出。
265.Clinical characteristics and immune profile alterations in vaccinated individuals with breakthrough Delta SARS-CoV-2 infections.
突破性三角洲SARS-CoV-2感染的疫苗接种者的临床特征和免疫概况改变。
266.Variance-quantitative trait loci enable systematic discovery of gene-environment interactions for cardiometabolic serum biomarkers.
变异定量性状位点能够系统发现心脏代谢血清生物标志物的基因-环境相互作用。
267.ADAMTS18+ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels.
ADAMTS18+绒毛顶端端细胞维持着极化的VEGFA信号域和吸收营养的肠道血管中的栅栏。
268.Mechanism of fertilization-induced auxin synthesis in the endosperm for seed and fruit development.
受精诱导的辅助素在胚乳中合成种子和果实发育的机制。
269.A Nodal enhanced micropeptide NEMEP regulates glucose uptake during mesendoderm differentiation of embryonic stem cells.
一种Nodal增强型微肽NEMEP调控胚胎干细胞中胚层分化过程中的葡萄糖摄取。
270.Probing strigolactone perception mechanisms with rationally designed small-molecule agonists stimulating germination of root parasitic weeds.
用合理设计的小分子激动剂探究刺激根寄生杂草发芽的糙米内酯感知机制。
271.Acetyl-CoA-Carboxylase 1-mediated de novo fatty acid synthesis sustains Lgr5+ intestinal stem cell function.
乙酰-CoA-羧基酶1介导的从头脂肪酸合成维持Lgr5+肠道干细胞的功能。
272.Ciliary transition zone proteins coordinate ciliary protein composition and ectosome shedding.
睫状体过渡区蛋白协调睫状体蛋白的组成和外植体的脱落。
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