【文献速递】【Nature medicine】【2022年】【1月】

声明：本专栏主要对生命科学领域的一些期刊文章标题进行翻译，所有内容均由本人手工整理翻译。由于本人专业为生物分析相关，其他领域如果出现翻译错误请谅解。

1. Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19

地塞米松调节严重COVID-19中的未成熟中性粒细胞和干扰素编程

2. Risk factors for PICU admission and death among children and young people hospitalized with COVID-19 and PIMS-TS in England during the first pandemic year

在大流行的第一年，英格兰因COVID-19和PIMS-TS住院的儿童和年轻人中PICU入院和死亡的危险因素

3. Deaths in children and young people in England after SARS-CoV-2 infection during the first pandemic year

在大流行的第一年感染SARS-CoV-2后英格兰儿童和年轻人的死亡人数

4. Real-time alerting system for COVID-19 and other stress events using wearable data

使用可穿戴数据的COVID-19和其他压力事件的实时警报系统

5. Direct antimicrobial resistance prediction from clinical MALDI-TOF mass spectra using machine learning

使用机器学习从临床MALDI-TOF质谱直接预测抗菌素耐药性

6. Artificial intelligence for diagnosis and Gleason grading of prostate cancer: the PANDA challenge

用于前列腺癌诊断和Gleason分级的人工智能：PANDA挑战

7. Atezolizumab with enzalutamide versus enzalutamide alone in metastatic castration-resistant prostate cancer: a randomized phase 3 trial

阿替唑单抗联合恩扎鲁胺治疗转移性去势耐受性前列腺癌与单独使用恩扎鲁酰胺治疗的比较：一项随机3期试验

8. Optimizing risk-based breast cancer screening policies with reinforcement learning

通过强化学习优化基于风险的乳腺癌筛查策略

9. Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency

生殖系DNA复制修复缺陷儿童对PD-1抑制反应的基因组预测因子

10. Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide

一种有效的混合主链反义寡核苷酸抑制突变C9orf72的表达

11. Antisense oligonucleotide silencing of FUS expression as a therapeutic approach in amyotrophic lateral sclerosis

FUS表达的反义寡核苷酸沉默作为肌萎缩侧索硬化症的治疗方法

12. Preclinical development and phase 1 trial of a novel siRNA targeting lipoprotein(a)

1种新型siRNA靶向脂蛋白（a）的临床前开发和1期试验

13. Subcutaneous infusion of exenatide and cardiovascular outcomes in type 2 diabetes: a non-inferiority randomized controlled trial

2型糖尿病皮下输注艾塞那肽和心血管结果：一项非劣效性随机对照试验

14. Long-term outcomes of lentiviral gene therapy for the β-hemoglobinopathies: the HGB-205 trial

β-血红蛋白病慢病毒基因治疗的长期结果：HGB-205试验

15. Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott–Aldrich syndrome

慢病毒造血干/祖细胞基因治疗Wiskott-Aldrich综合征的长期安全性和有效性

16. Lentiviral globin gene therapy with reduced-intensity conditioning in adults with β-thalassemia: a phase 1 trial

β-地中海贫血成人慢病毒珠蛋白基因治疗降低强度调节：1期试验

17. Hemolysis contributes to anemia during long-duration space flight

在长时间的太空飞行中溶血会导致贫血

18. A guide to immunotherapy for COVID-19

COVID-19 免疫治疗指南

19. AI in health and medicine

健康和医学中的人工智能