百萤Cy5叠氮化物-----用于荧光成像的花青染料
1.百萤Cy5叠氮化物作用
Cy5叠氮化物已用于标记生物分子，用于荧光成像和其他基于荧光的生化分析。它们广泛用于标记肽，蛋白质和寡核苷酸等。Cy5 染料是常见的红色荧光团中的一种。这些多功能荧光团可以耐受3-10的pH范围，用于生物相关pH的各种应用。该染料还具有DMSO耐受性和光稳定性，能够在不损失性能的情况下从储存转移至分析。水溶性在测定缓冲液中对有机溶剂的需要。我们的Cy5染料经过QC测试，可确保高水平的发色团和活性染料含量。单活性染料适用于蛋白质和寡核苷酸的靶向，标记，双活性染料更适合于一般标记。建议使用NHS酯染料标记胺基，建议使用马来酰亚胺染料标记硫醇基团。该Cy5 叠氮化物选择性地与炔基反应。
2.百萤Cy5叠氮化物参数
Ex(nm) 651
Em(nm) 670
分 子 量 838.91
溶 剂 DMSO
储存条件 保存在(＜-15℃),尽量避免光照
保 质 期 12个月
外 观 蓝色固体
3. 百萤Cy5叠氮化物物理性质
校正系数(260nm) 0.02
校正系数(280nm) 0.03
校正系数(482nm) 0.009
校正系数(565nm) 0.09
激 发(nm) 651
排放量(nm) 670
4.百萤Cy5叠氮化物参考文献
Cube-shaped theranostic paclitaxel prodrug nanocrystals with surface functionalization of SPC and MPEG-DSPE for imaging and chemotherapy
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Thermo-sensitive hydrogel PLGA-PEG-PLGA as a vaccine delivery system for intramuscular immunization
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Affinity-Controlled Protein Encapsulation into Sub-30 nm Telodendrimer Nanocarriers by Multivalent and Synergistic Interactions
Authors: Xu Wang, Changying Shi, Li Zhang, Alexa Bodman, Dandan Guo, Lili Wang, Walter A Hall, Stephan Wilkens, Juntao Luo
Journal: Biomaterials (2016)
Carboxymethyl Dextran-Stabilized Polyethylenimine-Poly (epsilon-caprolactone) Nanoparticles-Mediated Modulation of MicroRNA-34a Expression via Small-Molecule Modulator for Hepatocellular Carcinoma Therapy
Authors: Xiongwei Deng, Zhaoxia Yin, Zhixiang Zhou, Yihui Wang, Fang Zhang, Qin Hu, Yishu Yang, Jianqing Lu, Yan Wu, Wang Sheng
Journal: ACS applied materials & interfaces (2016): 17068--17079
Click-electron microscopy for imaging metabolically tagged nonprotein biomolecules
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Journal: Nat Chem Biol (2016): 459--465
Design, synthesis and evaluation of VEGF-siRNA/CRS as a novel vector for gene delivery
Authors: Wen Zhao, Yifan Zhang, Xueyun Jiang, Chunying Cui
Journal: Drug Design, Development and Therapy (2016): 3851
Molecular Basis and Consequences of the Cytochrome c-tRNA Interaction
Authors: Cuiping Liu, Aaron J Stonestrom, Thomas Christian, Jeongsik Yong, Ryuichi Takase, Ya-Ming Hou, Xiaolu Yang
Journal: Journal of Biological Chemistry (2016): 10426--10436
Determination of the active transport of fucoidan derived from okinawa mozuku across the human intestinal caco-2 cells as assessed by size-exclusion chromatography
Authors: Takeaki Nagamine, Kou Hayakawa, Kyoumi Nakazato, Masahiko Iha
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