活性氧Chebulic Acid，CAS No. 23725-05-5

产品名称：活性氧Chebulic Acid，CAS No. 23725-05-5

产地：西安

规格：1mg 5mg 10mg

纯度：99%

用途：仅用于科研

状态：固体/粉末

储藏条件：冷藏-20℃

温馨提示：仅用于科研，不能用于人体实验！

说明：提供使用说明，核磁图谱，包装，价格，产地，制备方法，应用，稳定性，溶解度，简单合成等各种信息　　

Chebulic acid is a phenol that has been found in T. chebular and has diverse biological activities.It reduces production of reactive oxygen species (ROS) in human umbilical vein endothelial cells (HUVECs) induced by glyceraldehyde-related advanced glycation end products (glycer-AGEs) when used at a concentration of 100 µg/ml.1 Chebulic acid reduces glycer-AGE-induced adhesion of HUVECs to THP-1 monocytes. It induces Nrf2 nuclear translocation and glutathione (GSH) synthesis and inhibits glycer-AGE-induced collagen accumulation, a marker of fibrosis, in LX-2 hepatic stellate cells.In vivo, chebulic acid (25 and 50 mg/kg) increases serum insulin levels and reduces blood urea nitrogen levels, proteinuria, albuminuria, and serum glucose levels in a diabetic rat model of ischemia-reperfusion-induced nephropathy.

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编辑：XAQYBIO HAO，2023年4月20日。