【标题速读】【Ncomm】【biological-sciences】【2022年】【6月】
声明：本专栏主要对生命科学领域的一些期刊文章标题进行翻译，所有内容均由本人手工整理翻译。由于本人专业为生物分析相关，其他领域如果出现翻译错误请谅解。
1.Reconstruction of a catalogue of genome-scale metabolic models with enzymatic constraints using GECKO 2.0.
使用GECKO 2.0重建具有酶学约束的基因组尺度的代谢模型目录。
2.Simple synthesis of massively parallel RNA microarrays via enzymatic conversion from DNA microarrays.
通过对DNA芯片的酶促转换，简单合成大规模并行的RNA芯片。
3.Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state.
通过改变构象状态对PPM1D丝氨酸/苏氨酸磷酸酶进行异生抑制。
4.An essential role for tungsten in the ecology and evolution of a previously uncultivated lineage of anaerobic, thermophilic Archaea.
钨在厌氧、嗜热古菌的生态学和进化中的重要作用。
5.Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing.
利用TALEN基因编辑技术赋予通用CAR T细胞以免疫破坏特性。
6.Comparative genomics of Acinetobacter baumannii and therapeutic bacteriophages from a patient undergoing phage therapy.
鲍曼不动杆菌和治疗性噬菌体的比较基因组学，来自于一个接受噬菌体治疗的病人。
7.Tight junction channel regulation by interclaudin interference.
细胞间干扰的紧密连接通道调节。
8.Trans-cellular tunnels induced by the fungal pathogen Candida albicans facilitate invasion through successive epithelial cells without host damage.
真菌病原体白色念珠菌诱导的跨细胞隧道有利于在没有宿主损伤的情况下通过连续的上皮细胞入侵。
9.Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots.
内脏、腹部皮下和臀部脂肪库的遗传基础。
10.Effect of vaccination on household transmission of SARS-CoV-2 Delta variant of concern.
疫苗接种对SARS-CoV-2 Delta变体家庭传播的影响值得关注。
11.CD8+T cell responsiveness to anti-PD-1 is epigenetically regulated by Suv39h1 in melanomas.
CD8+T细胞对抗PD-1的反应性在黑色素瘤中受到Suv39h1的表观调节。
12.Inactivation of the Hippo tumor suppressor pathway promotes melanoma.
Hippo肿瘤抑制通路的失活促进黑色素瘤的发生。
13.Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277.
ML277调控KCNQ1通道电流的结构和电生理学基础。
14.Reply to: Pitfalls in using phenanthroline to study the causal relationship between promoter nucleosome acetylation and transcription.
回复： 使用菲罗啉研究启动子核糖体乙酰化和转录之间因果关系的陷阱。
15.Pitfalls in using phenanthroline to study the causal relationship between promoter nucleosome acetylation and transcription.
使用菲罗啉研究启动子核糖体乙酰化和转录之间的因果关系的陷阱。
16.Pervasive translation of circular RNAs driven by short IRES-like elements.
由短的IRES样元素驱动的环状RNA的普遍翻译。
17.Vertex protein PduN tunes encapsulated pathway performance by dictating bacterial metabolosome morphology.
顶点蛋白PduN通过支配细菌代谢体的形态来调整封装途径的性能。
18.A guided multiverse study of neuroimaging analyses.
神经影像分析的指导下的多宇宙研究。
19.The genetic heterogeneity and drug resistance mechanisms of relapsed refractory multiple myeloma.
复发难治性多发性骨髓瘤的遗传异质性和耐药机制。
20.Rhythmic interactions between the mediodorsal thalamus and prefrontal cortex precede human visual perception.
丘脑内侧和前额叶皮层之间的节律性相互作用先于人类视觉感知。
21.The genetic architecture of pneumonia susceptibility implicates mucin biology and a relationship with psychiatric illness.
肺炎易感性的遗传结构牵涉到粘液蛋白生物学以及与精神病的关系。
22.Limited effects of m6A modification on mRNA partitioning into stress granules.
m6A修饰对mRNA分配到应激颗粒的有限影响。
23.SARS-CoV-2 antibody trajectories after a single COVID-19 vaccination with and without prior infection.
单次COVID-19疫苗接种后的SARS-CoV-2抗体轨迹，有无先前感染。
24.WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage.
WASp调节单链DNA上的RPA功能以应对复制压力和DNA损伤。
25.Distinct nociception processing in the dysgranular and barrel regions of the mouse somatosensory cortex.
小鼠体感皮层障碍区和桶状区的不同痛觉处理。
26.Regulation of age-associated insulin resistance by MT1-MMP-mediated cleavage of insulin receptor.
MT1-MMP介导的胰岛素受体裂解对年龄相关的胰岛素抵抗的调节。
27.Host lung microbiota promotes malaria-associated acute respiratory distress syndrome.
宿主肺部微生物群促进疟疾相关的急性呼吸窘迫综合征。
28.Heat-fueled enzymatic cascade for selective oxyfunctionalization of hydrocarbons.
碳氢化合物选择性氧功能化的热助推酶级联反应。
29.TPGS-based and S-thanatin functionalized nanorods for overcoming drug resistance in Klebsiella pneumonia.
基于TPGS和S-thanatin的功能化纳米棒克服肺炎克雷伯菌的抗药性.
30.Deep learning to diagnose Hashimoto’s thyroiditis from sonographic images.
深度学习从声像图中诊断桥本甲状腺炎.
31.Reply to: “Steller’s sea cow uncertain history illustrates importance of ecological context when interpreting demographic histories from genomes”.
回复： "斯特勒海牛不确定的历史说明了从基因组解释人口历史时生态环境的重要性"。
32.Network-based machine learning approach to predict immunotherapy response in cancer patients.
基于网络的机器学习方法来预测癌症患者的免疫治疗反应。
33.Structural basis for mitoguardin-2 mediated lipid transport at ER-mitochondrial membrane contact sites.
mitoguardin-2在ER-mitochondrial膜接触点介导脂质运输的结构基础。
34.Lsm7 phase-separated condensates trigger stress granule formation.
Lsm7相分离的凝集物引发应激颗粒的形成。
35.The genomic basis of the plant island syndrome in Darwin’s giant daisies.
达尔文巨型雏菊的植物岛屿综合征的基因组基础。
36.The impact of rare germline variants on human somatic mutation processes.
罕见生殖系变体对人类体细胞突变过程的影响。
37.SpySwitch enables pH- or heat-responsive capture and release for plug-and-display nanoassembly.
SpySwitch实现了pH值或热反应的捕获和释放，用于插拔式纳米组装。
38.Pancreatic α and β cells are globally phase-locked.
胰腺α和β细胞是全球锁相的。
39.SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination.
SHLD1对53BP1依赖的V(D)J重组是可有可无的，但对生产性的类转换重组至关重要。
40.Immunogenicity and reactogenicity of SARS-CoV-2 vaccines BNT162b2 and CoronaVac in healthy adolescents.
SARS-CoV-2疫苗BNT162b2和CoronaVac对健康青少年的免疫原性和反应原性。
41.Evolution and activation mechanism of the flavivirus class II membrane-fusion machinery.
黄病毒II类膜融合机制的演变和激活机制。
42.Senescent cells limit p53 activity via multiple mechanisms to remain viable.
衰老的细胞通过多种机制限制p53的活性以保持活力。
43.A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery.
在没有mATG8结合机制的情况下，降解型到分泌型的自噬开关介导了线粒体的清除。
44.MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma.
MYCN驱动的脂肪酸摄取是神经母细胞瘤的一个代谢弱点。
45.Maternal immune response and placental antibody transfer after COVID-19 vaccination across trimester and platforms.
COVID-19疫苗接种后的母体免疫反应和胎盘抗体转移跨越三个月和平台。
46.Learning representations of chromatin contacts using a recurrent neural network identifies genomic drivers of conformation.
使用递归神经网络学习染色质接触的表征，确定构象的基因组驱动因素。
47.Clonal reconstruction from co-occurrence of vector integration sites accurately quantifies expanding clones in vivo.
从载体整合点的共同出现中进行克隆重建，准确地量化了体内的扩展克隆。
48.Lentivector cryptic splicing mediates increase in CD34+ clones expressing truncated HMGA2 in human X-linked severe combined immunodeficiency.
慢病毒隐性剪接介导了人类X连锁严重联合免疫缺陷症中表达截断的HMGA2的CD34+克隆的增加。
49.Glutamine deficiency in solid tumor cells confers resistance to ribosomal RNA synthesis inhibitors.
固体肿瘤细胞中谷氨酰胺的缺失赋予了对核糖体RNA合成抑制剂的抗性。
50.Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records.
10个英国纵向研究和电子健康记录中的长期COVID负担和风险因素。
51.High-dimensional profiling reveals Tc17 cell enrichment in active Crohn’s disease and identifies a potentially targetable signature.
高维分析揭示了Tc17细胞在活动性克罗恩病中的富集，并确定了一个潜在的目标特征。
52.Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity.
死于铁中毒的癌细胞阻碍了树突状细胞介导的抗肿瘤免疫力。
53.Context-aware deconvolution of cell–cell communication with Tensor-cell2cell.
用Tensor-cell2cell对细胞-细胞通讯进行上下文感知的去卷积。
54.GenomicSuperSignature facilitates interpretation of RNA-seq experiments through robust, efficient comparison to public databases.
GenomicSuperSignature通过与公共数据库进行有力、有效的比较，促进了对RNA-seq实验的解释。
55.G1/S restriction point coordinates phasic gene expression and cell differentiation.
G1/S限制点协调了阶段性基因表达和细胞分化。
56.The importance of DNAPKcs for blunt DNA end joining is magnified when XLF is weakened.
当XLF被削弱时，DNAPKcs对钝性DNA末端连接的重要性被放大。
57.Laboratory evolution of synthetic electron transport system variants reveals a larger metabolic respiratory system and its plasticity.
合成电子运输系统变体的实验室进化揭示了一个更大的代谢呼吸系统及其可塑性。
58.Light-induced charge generation in polymeric nanoparticles restores vision in advanced-stage retinitis pigmentosa rats.
聚合物纳米颗粒中光诱导的电荷生成可恢复晚期视网膜色素变性大鼠的视力。
59.A patatin-like phospholipase mediates Rickettsia parkeri escape from host membranes.
一种类似蛋白酶的磷脂酶介导帕克特氏菌从宿主膜上逃脱。
60.Poor outcome of pediatric patients with acute myeloid leukemia harboring high FLT3/ITD allelic ratios.
携带高FLT3/ITD等位基因的儿童急性骨髓性白血病患者的不良后果。
61.Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency.
人类VLCAD缺乏症中突变酶的膜靶向缺陷的结构基础。
62.Frequency and mechanisms of LINE-1 retrotransposon insertions at CRISPR/Cas9 sites.
CRISPR/Cas9位点上LINE-1逆转录纺子插入的频率和机制。
63.Common genetic variation associated with Mendelian disease severity revealed through cryptic phenotype analysis.
通过隐性表型分析揭示与孟德尔疾病严重程度相关的常见遗传变异。
64.Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.
组合免疫疗法克服三阴性乳腺癌中MYC驱动的免疫规避。
65.Hsp multichaperone complex buffers pathologically modified Tau.
Hsp多介质复合体缓冲病理改变的Tau。
66.The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia.
22q11.2区域调控与精神分裂症有关的突触前基因产物。
67.Osteocyte CIITA aggravates osteolytic bone lesions in myeloma.
骨细胞CIITA加重骨髓瘤的溶骨性病变。
68.Molecular mechanics underlying flat-to-round membrane budding in live secretory cells.
活体分泌细胞中平膜向圆膜出芽的分子力学原理。
69.Warming-induced increase in carbon uptake is linked to earlier spring phenology in temperate and boreal forests.
暖化诱导的碳吸收增加与温带和北方森林的春季物候学提前有关。
70.A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination.
基于GPCR的酵母生物传感器用于生物医学、生物技术和使用点的大麻素测定。
71.Recovery of neural dynamics criticality in personalized whole-brain models of stroke.
在个性化的中风全脑模型中恢复神经动力学的临界点。
72.POLYRETINA restores light responses in vivo in blind Göttingen minipigs.
POLYRETINA恢复了哥廷根迷你猪体内的光反应。
73.Echolocation-related reversal of information flow in a cortical vocalization network.
皮质发声网络中与回声定位有关的信息流的逆转。
74.Existing function in primary visual cortex is not perturbed by new skill acquisition of a non-matched sensory task.
初级视觉皮层的现有功能不受非匹配的感觉任务的新技能获取的干扰。
75.Occult polyclonality of preclinical pancreatic cancer models drives in vitro evolution.
临床前胰腺癌模型的隐性多克隆性驱动体外进化。
76.Detection of SARS-CoV-2 intra-host recombination during superinfection with Alpha and Epsilon variants in New York City.
在纽约市Alpha和Epsilon变体的超级感染中检测SARS-CoV-2的宿主内重组。
77.FANCM promotes class I interfering crossovers and suppresses class II non-interfering crossovers in wheat meiosis.
FANCM促进小麦减数分裂中的I类干扰性交叉，抑制II类非干扰性交叉。
78.Microtubule disassembly by caspases is an important rate-limiting step of cell extrusion.
卡西普酶对微管的分解是细胞挤压的一个重要限速步骤。
79.Emergent properties as by-products of prebiotic evolution of aminoacylation ribozymes.
氨基酰化核糖核酸酶的新兴特性是生物前进化的副产品。
80.Mucin induces CRISPR-Cas defense in an opportunistic pathogen.
粘液蛋白诱导机会主义病原体的CRISPR-Cas防御。
81.The force required to remove tubulin from the microtubule lattice by pulling on its α-tubulin C-terminal tail.
通过拉动其α-管蛋白的C端尾巴将管蛋白从微管格子中移除所需的力。
82.Structural mechanism of protein recognition by the FW domain of autophagy receptor Nbr1.
自噬受体Nbr1的FW结构域识别蛋白质的结构机制。
83.Assembly dynamics of FtsZ and DamX during infection-related filamentation and division in uropathogenic E. coli.
FtsZ和DamX在尿毒症大肠杆菌感染相关成丝和分裂过程中的组装动力学。
84.Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation.
用咪唑类吲哚靶向真菌膜平衡，损害唑类抗性和生物膜形成。
85.COVID-19 disease severity in US Veterans infected during Omicron and Delta variant predominant periods.
美国退伍军人在Omicron和Delta变体主导时期感染的COVID-19疾病严重程度。
86.Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.
Wiskott-Aldrich综合征蛋白形成核凝聚物并调控替代剪接。
87.Ru(II) photocages enable precise control over enzyme activity with red light.
Ru(II)光笼能够用红光精确控制酶的活性。
88.Age and sex-specific risks of myocarditis and pericarditis following Covid-19 messenger RNA vaccines.
Covid-19信使RNA疫苗后心肌炎和心包炎的年龄和性别特定风险。
89.Cell surface glycan engineering reveals that matriglycan alone can recapitulate dystroglycan binding and function.
细胞表面糖类工程显示，单独的基质聚糖可以重现抗肌萎缩聚糖的结合和功能。
90.Chain flexibility of medicinal lipids determines their selective partitioning into lipid droplets.
药用脂质的链的灵活性决定了它们在脂质液滴中的选择性分配。
91.Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression.
胶质瘤异质性的时空分析显示COL1A1是破坏肿瘤进展的一个可操作的目标。
92.DNA damage-induced transcription stress triggers the genome-wide degradation of promoter-bound Pol II.
DNA损伤诱导的转录压力引发了启动子结合的Pol II的全基因组降解。
93.Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level.
内皮细胞异质性和小胶质细胞调节器在单细胞水平上被猪细胞景观所揭示。
94.Sizing up DNA nanostructure assembly with native mass spectrometry and ion mobility.
用原生质谱和离子迁移率对DNA纳米结构组装进行测定。
95.Coordination of metal center biogenesis in human cytochrome c oxidase.
人类细胞色素c氧化酶中金属中心生物生成的协调。
96.A glycine-rich PE_PGRS protein governs mycobacterial actin-based motility.
一个富含甘氨酸的PE_PGRS蛋白控制着霉菌基于肌动蛋白的运动。
97.A microfluidic optimal experimental design platform for forward design of cell-free genetic networks.
用于无细胞遗传网络正向设计的微流控最佳实验设计平台。
98.The encephalomyocarditis virus Leader promotes the release of virions inside extracellular vesicles via the induction of secretory autophagy.
脑膜炎病毒Leader通过诱导分泌型自噬促进细胞外囊泡内病毒的释放。
99.A structural and functional subdivision in central orbitofrontal cortex.
中部眶额皮层的结构和功能分区。
100.Insights into the mechanism of action of the arbitrium communication system in SPbeta phages.
洞察SPbeta噬菌体中的套圈通信系统的作用机制。
101.Construction of a synthetic Saccharomyces cerevisiae pan-genome neo-chromosome.
合成的酿酒酵母泛基因组新染色体的构建。
102.Contribution of low population immunity to the severe Omicron BA.2 outbreak in Hong Kong.
低人口免疫力对香港严重的Omicron BA.2疫情的贡献。
103.Porphyrin as a versatile visible-light-activatable organic/metal hybrid photoremovable protecting group.
卟啉作为一种多功能的可见光可激活的有机/金属混合光可移动的保护基。
104.Results of the phase I CCTG IND.231 trial of CX-5461 in patients with advanced solid tumors enriched for DNA-repair deficiencies.
CX-5461在富含DNA修复缺陷的晚期实体瘤患者中的I期CCTG IND.231试验的结果。
105.Neutralization of Omicron BA.1, BA.2, and BA.3 SARS-CoV-2 by 3 doses of BNT162b2 vaccine.
3剂BNT162b2疫苗对Omicron BA.1, BA.2, 和BA.3 SARS-CoV-2的中和作用。
106.Substrate binding in the mitochondrial ADP/ATP carrier is a step-wise process guiding the structural changes in the transport cycle.
线粒体ADP/ATP载体中的底物结合是一个指导运输循环结构变化的分步过程。
107.Engineering substrate specificity of HAD phosphatases and multienzyme systems development for the thermodynamic-driven manufacturing sugars.
HAD磷酸酶的底物特异性工程和热力学驱动的制造糖类的多酶系统开发。
108.Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation.
转录因子驱动的细胞周期退出和体内粒细胞分化过程中的线状特化的协调。
109.Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR.
大循环稳定其与14-3-3的相互作用增加CFTR的质膜定位和活性。
110.Probing TDP-43 condensation using an in silico designed aptamer.
使用计算机设计的适体探测 TDP-43 凝聚。
111.Bateman gradients from first principles.
来自第一原理的贝特曼梯度。
112.HOX epimutations driven by maternal SMCHD1/LRIF1 haploinsufficiency trigger homeotic transformations in genetically wildtype offspring.
由母体SMCHD1/LRIF1单倍体不足驱动的HOX外显子引发基因野生型后代的顺行性转变。
113.Coiled-coil heterodimer-based recruitment of an exonuclease to CRISPR/Cas for enhanced gene editing.
基于盘状线圈的异构体对CRISPR/Cas的外切酶进行招募以增强基因编辑。
114.Gut virome profiling identifies a widespread bacteriophage family associated with metabolic syndrome.
肠道病毒谱分析确定了一个与代谢综合征有关的广泛的噬菌体家族。
115.The obligate intracellular bacterium Orientia tsutsugamushi differentiates into a developmentally distinct extracellular state.
强制性细胞内细菌Orientia tsutsugamushi分化为发育不同的细胞外状态。
116.A broadly neutralizing antibody protects Syrian hamsters against SARS-CoV-2 Omicron challenge.
一种广谱中和抗体保护叙利亚仓鼠免受SARS-CoV-2 Omicron挑战。
117.An intein-split transactivator for intersectional neural imaging and optogenetic manipulation.
一种用于交叉神经成像和光遗传学操作的内含肽分裂反式激活因子。
118.Mnemonic construction and representation of temporal structure in the hippocampal formation.
海马形成中记忆的构建和时间结构的表示。
119.hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells.
hnRNPH1招募PTBP2和SRSF3以调控生殖细胞的替代剪接。
120.In situ 3D bioprinting with bioconcrete bioink.
用生物混凝土生物墨水进行原位3D生物打印。
121.Peripherally restricted transthyretin-based delivery system for probes and therapeutics avoiding opioid-related side effects.
基于外周限制性转甲状腺素的探针和治疗药物的输送系统，避免了阿片类药物的相关副作用。
122.Advancing our understanding of genetic risk factors and potential personalized strategies for pelvic organ prolapse.
推进我们对盆腔器官脱垂的遗传风险因素和潜在个性化策略的理解。
123.High-resolution mass measurements of single budding yeast reveal linear growth segments.
单个发芽酵母的高分辨率质量测量揭示了线性生长段。
124.RNase III-CLASH of multi-drug resistant Staphylococcus aureus reveals a regulatory mRNA 3′UTR required for intermediate vancomycin resistance.
多重耐药金黄色葡萄球菌的RNase III-CLASH揭示了中间万古霉素抗性所需的调节性mRNA 3′UTR。
125.RNase III CLASH in MRSA uncovers sRNA regulatory networks coupling metabolism to toxin expression.
MRSA的RNase III CLASH发现了连接代谢和毒素表达的sRNA调节网络。
126.Branched actin networks are organized for asymmetric force production during clathrin-mediated endocytosis in mammalian cells.
哺乳动物细胞中克拉特林介导的内吞过程中，分支的肌动蛋白网络被组织起来以产生不对称的力量。
127.Host control and the evolution of cooperation in host microbiomes.
宿主控制和宿主微生物组中合作的进化。
128.Dissociation between individual differences in self-reported pain intensity and underlying fMRI brain activation.
自我报告的疼痛强度的个体差异与基础fMRI大脑激活之间的关联。
129.Kir2.1-mediated membrane potential promotes nutrient acquisition and inflammation through regulation of nutrient transporters.
Kir2.1介导的膜电位通过调节营养物质转运体促进营养物质的获取和炎症的发生。
130.Cyclic microchip assay for measurement of hundreds of functional proteins in single neurons.
用于测量单个神经元中数百种功能蛋白的循环芯片检测。
a 通过 MIST 微珠阵列分析多种蛋白质的 CycMIST 过程示意图。 b 在对应于 PDMS 微孔的 MIST 阵列的每个 75 μm × 75 μm 区域上寡聚 DNA 包被微珠的数量分布，n = 3 独立 MIST 阵列。 c 同一 MIST 阵列上同种寡聚 DNA 包被微珠的数量分布，n = 5 独立 MIST 阵列。 d 通过改变 MIST 阵列上 50 种生物素化互补寡 DNA 的浓度来表征 CycMIST 灵敏度，n = 10 次独立实验。 除了细胞加载和结合结合外，这与单细胞蛋白质检测实验中的程序相同。 e 4 个解码周期和 3 种荧光染料（Alexa Fluor 488、Cy3 和 Cy5）的荧光强度一致性，n = 5 个独立实验。 f 通过 CycMIST 对单个细胞中的 50 种蛋白质进行多重分析的样本图像和 4 个解码循环图像。 灰度图像是蛋白质检测结果，彩色图像是从第 1 周期到第 4 周期的解码周期。底部面板是上面板中方块的放大图像。 比例尺：20 μm（上图）； 5 微米（下图）。
131.The antenna of far-red absorbing cyanobacteria increases both absorption and quantum efficiency of Photosystem II.
吸收远红的蓝藻的触角增加了光系统II的吸收和量子效率。
132.NANOG initiates epiblast fate through the coordination of pluripotency genes expression.
NANOG通过协调多能性基因的表达来启动外胚层命运。
133.Binding and structural basis of equine ACE2 to RBDs from SARS-CoV, SARS-CoV-2 and related coronaviruses.
马匹ACE2与SARS-CoV、SARS-CoV-2和相关冠状病毒的RBDs的结合和结构基础。
134.Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance.
定义SARS-CoV-2主要蛋白酶的底物包膜以预测和避免抗药性。
135.A scalable, open-source implementation of a large-scale mechanistic model for single cell proliferation and death signaling.
一个可扩展的、开源的单细胞增殖和死亡信号的大规模机制模型的实现。
136.Innate immune responses against the fungal pathogen Candida auris.
针对真菌病原体Candida auris的先天免疫反应。
137.MicroRNA-21 promotes pancreatic β cell function through modulating glucose uptake.
MicroRNA-21通过调节葡萄糖摄取促进胰腺β细胞功能。
138.A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood.
多民族多基因风险评分与高血压患病率和整个成年后的发展有关。
139.Islet autoantibody seroconversion in type-1 diabetes is associated with metagenome-assembled genomes in infant gut microbiomes.
1型糖尿病患者的胰岛自身抗体血清转换与婴儿肠道微生物组的元基因组有关。
140.Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase.
病毒性RNA聚合酶识别模板链脱氧尿苷启动子的结构基础。
141.Mapping the conformational energy landscape of Abl kinase using ClyA nanopore tweezers.
使用ClyA纳米孔镊子绘制Abl激酶的构象能量图。
142.Revealing the human mucinome.
揭示人类粘液组的情况。
143.Optimal CD8+ T cell effector function requires costimulation-induced RNA-binding proteins that reprogram the transcript isoform landscape.
最佳的CD8+T细胞效应功能需要成本刺激诱导的RNA结合蛋白来重新规划转录本的异构体景观。
144.Global stable-isotope tracing metabolomics reveals system-wide metabolic alternations in aging Drosophila.
全球稳定同位素追踪代谢组学揭示了衰老果蝇的全系统代谢变化。
145.Satellite repeat transcripts modulate heterochromatin condensates and safeguard chromosome stability in mouse embryonic stem cells.
卫星重复转录物调节小鼠胚胎干细胞中的异染色质凝聚物并保障染色体稳定性。
146.Inhibition of negative feedback for persistent epithelial cell–cell junction contraction by p21-activated kinase 3.
p21激活的激酶3对持久性上皮细胞-细胞交界处收缩的负反馈的抑制。
147.Forest Fire Clustering for single-cell sequencing combines iterative label propagation with parallelized Monte Carlo simulations.
用于单细胞测序的Forest Fire Clustering结合了迭代标签传播和并行蒙特卡洛模拟。
148.HarmonizR enables data harmonization across independent proteomic datasets with appropriate handling of missing values.
HarmonizR能够在独立的蛋白质组数据集之间进行数据协调，并对缺失值进行适当处理。
149.EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment.
EphB4和ephrinB2在头颈部肿瘤微环境中作用相反。
150.SARS-CoV-2 Omicron variant causes mild pathology in the upper and lower respiratory tract of hamsters.
SARS-CoV-2 Omicron变体在仓鼠上、下呼吸道引起轻度病变。
151.Diagonal integration of multimodal single-cell data: potential pitfalls and paths forward.
多模态单细胞数据的对角线整合：潜在的陷阱和前进的道路。
152.A global forum on synthetic biology: the need for international engagement.
关于合成生物学的全球论坛：需要国际参与。
153.Chromosome-level and haplotype-resolved genome provides insight into the tetraploid hybrid origin of patchouli.
染色体水平和单倍型解析的基因组为了解广藿香的四倍体杂交起源提供了线索。
154.Complex regulation of Gephyrin splicing is a determinant of inhibitory postsynaptic diversity.
Gephyrin拼接的复杂调节是抑制性突触后多样性的决定因素。
155.Peptide fusion improves prime editing efficiency.
肽融合提高了质粒编辑效率。
156.Bioorthogonally activatable cyanine dye with torsion-induced disaggregation for in vivo tumor imaging.
用于体内肿瘤成像的具有扭转诱导分解作用的生物正交可激活的青色染料。
157.A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes.
2型糖尿病患者BCAA分解代谢的药理激活的随机安慰剂对照临床试验。
158.RIViT-seq enables systematic identification of regulons of transcriptional machineries.
RIViT-seq能够系统地识别转录机制的调节子。
159.The architecture and operating mechanism of a cnidarian stinging organelle.
刺胞器的结构和运行机制。
160.3D structure and in situ arrangements of CatSper channel in the sperm flagellum.
精子鞭毛中CatSper通道的三维结构和原位排列。
161.Comparative parallel multi-omics analysis during the induction of pluripotent and trophectoderm states.
在诱导多能体和滋养体状态的过程中进行比较性的平行多组学分析。
162.Asynchronous glutamate release is enhanced in low release efficacy synapses and dispersed across the active zone.
异步谷氨酸释放在低释放效能的突触中得到加强，并分散在整个活动区。
163.Cryo-EM structure of an amyloid fibril formed by full-length human SOD1 reveals its conformational conversion.
全长人SOD1形成的淀粉样纤维的冷冻电镜结构揭示了其构象转换。
164.Bifurcation drives the evolution of assembly-line biosynthesis.
分叉推动了流水线生物合成的进化。
165.Core and rod structures of a thermophilic cyanobacterial light-harvesting phycobilisome.
嗜热型蓝藻采光藻体的核心和杆状结构。
166.Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction.
内源性大麻素合成酶DAGLB的缺陷导致了早发性帕金森病和小鼠黑质多巴胺能神经元的功能障碍。
167.FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion.
FUNDC2通过抑制MFN1介导的线粒体融合促进肝脏肿瘤的发生。
168.The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin.
染色质重塑剂ATRX以随机的方式在异染色质和超染色质中促进各种核过程。
169.ZFP281-BRCA2 prevents R-loop accumulation during DNA replication.
ZFP281-BRCA2在DNA复制过程中防止R环的积累。
170.Functional but not obligatory link between microsaccades and neural modulation by covert spatial attention.
微动与隐蔽空间注意的神经调控之间存在功能性但非强制性的联系。
171.A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants.
全球脂质图揭示了SARS-CoV-2变体之间保守的宿主依赖性因素。
172.Context-dependent enhancer function revealed by targeted inter-TAD relocation.
有针对性的TAD间迁移揭示了上下文依赖的增强器功能。
173.Adipocyte-derived kynurenine promotes obesity and insulin resistance by activating the AhR/STAT3/IL-6 signaling.
脂肪细胞衍生的犬尿喹啉通过激活AhR/STAT3/IL-6信号传导促进肥胖和胰岛素抵抗。
174.Addressing challenges with real-world synthetic control arms to demonstrate the comparative effectiveness of Pralsetinib in non-small cell lung cancer.
应对现实世界中合成控制臂的挑战，以证明普拉西尼在非小细胞肺癌中的比较有效性。
175.ARID1A loss derepresses a group of human endogenous retrovirus-H loci to modulate BRD4-dependent transcription.
ARID1A的缺失解除了对一组人类内源性逆转录病毒-H位点的抑制，以调节BRD4依赖的转录。
176.Unmixing for ultra-high-plex fluorescence imaging.
超高倍数荧光成像的未混合.
177.A hexa-species transcriptome atlas of mammalian embryogenesis delineates metabolic regulation across three different implantation modes.
哺乳动物胚胎发育的六种转录组图谱勾勒出三种不同植入模式下的代谢调节。
178.Therapeutic efficacy of combined active and passive immunization in ART-suppressed, SHIV-infected rhesus macaques.
主动和被动联合免疫对受ART抑制的SHIV感染猕猴的治疗效果。
179.T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles.
T细胞跨突触囊泡与构成性细胞外囊泡不同，携带更多的效应物内容。
180.Disentangling the genetic basis of rhizosphere microbiome assembly in tomato.
解读番茄根瘤微生物群组装的遗传基础。
181.The impact of species-wide gene expression variation on Caenorhabditis elegans complex traits.
物种范围内的基因表达变异对优雅凯诺虫复杂性状的影响。
182.Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine.
对BNT162b2 SARS-CoV-2 RNA疫苗的抗原特异性反应的单细胞分析。
183.Phasing analysis of lung cancer genomes using a long read sequencer.
使用长读测序仪对肺癌基因组进行相位分析。
184.The 3D architecture of the pepper genome and its relationship to function and evolution.
辣椒基因组的三维结构及其与功能和进化的关系。
185.GPI-anchored FGF directs cytoneme-mediated bidirectional contacts to regulate its tissue-specific dispersion.
GPI锚定的FGF指导细胞膜介导的双向接触以调节其组织特异性分散。
186.A sound approach to advancing healthcare systems: the future of biomedical acoustics.
推进医疗保健系统的合理方法：生物医学声学的未来。
187.Ly6D+Siglec-H+ precursors contribute to conventional dendritic cells via a Zbtb46+Ly6D+ intermediary stage.
Ly6D+Siglec-H+前体通过Zbtb46+Ly6D+中间阶段对常规树突状细胞的贡献。
188.Light-sheet photonic force optical coherence elastography for high-throughput quantitative 3D micromechanical imaging.
光片式光子力光学相干弹性成像技术用于高通量定量三维微机械成像。
189.Identifying plant genes shaping microbiota composition in the barley rhizosphere.
识别塑造大麦根茎层微生物群组成的植物基因。
190.Catalytical nano-immunocomplexes for remote-controlled sono-metabolic checkpoint trimodal cancer therapy.
催化性纳米免疫复合物用于远程控制的超声代谢检查点三联体癌症治疗。
191.Coordination chemogenetics for activation of GPCR-type glutamate receptors in brain tissue.
脑组织中GPCR型谷氨酸受体激活的协调化学遗传学。
192.Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma.
Bempegaldesleukin与nivolumab联合治疗转移性肉瘤患者的试验研究。
193.Terahertz thermal curve analysis for label-free identification of pathogens.
太赫兹热曲线分析用于病原体的无标签鉴定。
194.Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.
软组织和骨肉瘤患者管理中的临床基因组分析。
195.Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite.
进化分化的利什曼寄生虫中快速肌动蛋白动态的结构基础。
196.Sex-specific multi-level 3D genome dynamics in the mouse brain.
小鼠大脑中的性别特异性多层次三维基因组动态。
197.Remote solid cancers rewire hepatic nitrogen metabolism via host nicotinamide-N-methyltransferase.
远程实体癌通过宿主烟酰胺-N-甲基转移酶重构肝脏氮素代谢。
198.Disease modeling by efficient genome editing using a near PAM-less base editor in vivo.
利用体内近乎无PAM的碱基编辑器进行高效基因组编辑的疾病建模。
199.Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets.
软组织和骨肉瘤的临床测序勾勒出不同的基因组图谱和潜在的治疗目标。
200.Pre-existing antibody levels negatively correlate with antibody titers after a single dose of BBV152 vaccination.
预先存在的抗体水平与单剂量BBV152疫苗接种后的抗体滴度呈负相关。
201.Distributed genetic architecture across the hippocampal formation implies common neuropathology across brain disorders.
分布在整个海马形成的遗传结构意味着整个大脑疾病的共同神经病理学。
202.Complete biosynthetic pathway to the antidiabetic drug acarbose.
抗糖尿病药物阿卡波糖的完整生物合成途径。
203.Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes.
多发性骨髓瘤的遗传亚型与不同的致病表型和临床结果有关。
204.Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational folding.
共同翻译折叠过程中核糖体相关Hsp40-Hsp70伴侣的结构重塑。
205.CXCL4 synergizes with TLR8 for TBK1-IRF5 activation, epigenomic remodeling and inflammatory response in human monocytes.
CXCL4与TLR8协同促进TBK1-IRF5的激活、表观基因组重塑和人类单核细胞的炎症反应。
206.ChIP-Hub provides an integrative platform for exploring plant regulome.
ChIP-Hub为探索植物调控组提供了一个综合平台。
207.A role for ascorbate conjugates of (+)-catechin in proanthocyanidin polymerization.
(+)-儿茶素的抗坏血酸共轭物在原花青素聚合中的作用。
208.Ursodeoxycholic acid reduces antitumor immunosuppression by inducing CHIP-mediated TGF-β degradation.
熊去氧胆酸通过诱导CHIP介导的TGF-β降解减少抗肿瘤免疫抑制。
209.Morphological pseudotime ordering and fate mapping reveal diversification of cerebellar inhibitory interneurons.
形态学上的假时排序和命运图谱揭示了小脑抑制性神经元的多样化。
210.Programmable probiotics modulate inflammation and gut microbiota for inflammatory bowel disease treatment after effective oral delivery.
可编程益生菌在有效口服后调节炎症和肠道微生物群以治疗炎症性肠病。
211.Brain-wide reconstruction of inhibitory circuits after traumatic brain injury.
创伤性脑损伤后全脑抑制性电路的重建。
212.A multifunctional system for genome editing and large-scale interspecies gene transfer.
一个用于基因组编辑和大规模种间基因转移的多功能系统。
213.Cas9-induced large deletions and small indels are controlled in a convergent fashion.
Cas9诱导的大缺失和小缺失以一种收敛的方式被控制。
214.Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks.
甲型流感病毒在体内经历了以随机瓶颈为主导的区块化复制。
215.SpG and SpRY variants expand the CRISPR toolbox for genome editing in zebrafish.
SpG和SpRY变体扩展了斑马鱼基因组编辑的CRISPR工具箱。
216.Identification, discrimination and heterogeneity of fibroblasts.
成纤维细胞的识别、鉴别和异质性。
217.Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders.
大规模的基因组分析揭示了对跨循环系统疾病和神经系统疾病的多态性的见解。
218.Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation.
紧凑的IF2允许启动子tRNA容纳到P位点，并为核糖体的延伸提供了门槛。
219.Anatomy of Omicron BA.1 and BA.2 neutralizing antibodies in COVID-19 mRNA vaccinees.
剖析COVID-19 mRNA疫苗接种者的Omicron BA.1和BA.2中和抗体。
220.Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma.
个别导管原位癌病变的基因表达特征确定了与侵袭性导管癌进展相关的过程和生物标志物。
221.Asgard archaea shed light on the evolutionary origins of the eukaryotic ubiquitin-ESCRT machinery.
阿斯加德古菌揭示了真核生物泛素-ESCRT机制的进化起源。
222.Neurotoxic amyloidogenic peptides in the proteome of SARS-COV2: potential implications for neurological symptoms in COVID-19.
SARS-COV2蛋白质组中的神经毒性淀粉样肽：对COVID-19的神经系统症状的潜在影响。
223.Ribosome profiling reveals multiple roles of SecA in cotranslational protein export.
核糖体分析揭示了SecA在共翻译蛋白输出中的多种作用。
224.Triiodothyronine (T3) promotes brown fat hyperplasia via thyroid hormone receptor α mediated adipocyte progenitor cell proliferation.
三碘甲状腺素（T3）通过甲状腺激素受体α介导的脂肪细胞祖细胞增殖促进棕色脂肪增生。
225.Linking individual differences in human primary visual cortex to contrast sensitivity around the visual field.
将人类初级视觉皮层的个体差异与视野周围的对比敏感度联系起来。
226.High throughput, label-free isolation of circulating tumor cell clusters in meshed microwells.
高通量、无标签分离网状微孔中的循环肿瘤细胞群。
227.Defect engineering of layered double hydroxide nanosheets as inorganic photosensitizers for NIR-III photodynamic cancer therapy.
层状双氢氧化物纳米片的缺陷工程作为无机光敏剂用于NIR-III光动力癌症治疗。
228.Dynamic interaction of BRCA2 with telomeric G-quadruplexes underlies telomere replication homeostasis.
BRCA2与端粒G-四联体的动态互动是端粒复制平衡的基础。
229.Variants in ASPH cause exertional heat illness and are associated with malignant hyperthermia susceptibility.
ASPH中的变体引起劳累性热病，并与恶性高热病的易感性有关。
230.A long-acting interleukin-7, rhIL-7-hyFc, enhances CAR T cell expansion, persistence, and anti-tumor activity.
一种长效白细胞介素-7，rhIL-7-hyFc，增强了CAR T细胞的扩展、持久性和抗肿瘤活性。
231.A proteogenomic signature of age-related macular degeneration in blood.
血液中年龄相关性黄斑变性的蛋白质基因组特征。
232.Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa.
恶性疟原虫7G8挑战为非洲基于PfNF54的PfSPZ疫苗的疗效提供了保守的预测。
233.NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility.
NUP62定位于ALS/FTLD的病理集合体，有助于TDP-43的不溶性。
234.Enhancing bioreactor arrays for automated measurements and reactive control with ReacSight.
用ReacSight加强生物反应器阵列的自动测量和反应性控制。
235.Mechanism of glycogen synthase inactivation and interaction with glycogenin.
糖原合成酶失活的机制和与糖原蛋白的相互作用。
236.Structural basis of resistance to herbicides that target acetohydroxyacid synthase.
对针对乙酰羟酸合成酶的除草剂产生抗性的结构基础。
237.Photoredox catalytic radical fluorosulfonylation of olefins enabled by a bench-stable redox-active fluorosulfonyl radical precursor.
光氧化催化自由基氟磺化烯烃的作用，由一个稳定的氧化还原活性的氟磺化自由基前体促成。
238.Antigen glycosylation regulates efficacy of CAR T cells targeting CD19.
抗原糖基化调节靶向CD19的CAR T细胞的疗效。
239.A highly conserved core bacterial microbiota with nitrogen-fixation capacity inhabits the xylem sap in maize plants.
具有固氮能力的高度保守的核心细菌微生物群栖息在玉米植物的木质部汁液中。
240.Expansion of cytotoxic tissue-resident CD8+ T cells and CCR6+CD161+ CD4+ T cells in the nasal mucosa following mRNA COVID-19 vaccination.
mRNA COVID-19疫苗接种后细胞毒性组织驻留CD8+T细胞和CCR6+CD161+CD4+T细胞在鼻粘膜的扩增。
241.Exploring the cellular landscape of circular RNAs using full-length single-cell RNA sequencing.
利用全长的单细胞RNA测序技术探索环状RNA的细胞景观。
242.Stable choice coding in rat frontal orienting fields across model-predicted changes of mind.
大鼠额叶定向区的稳定选择编码跨越模型预测的心智变化。
243.Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder.
Orgo-Seq整合了单细胞和批量转录组数据，以确定与自闭症谱系障碍相关的细胞类型特定驱动基因。
244.Deep learning driven biosynthetic pathways navigation for natural products with BioNavi-NP.
利用BioNavi-NP进行深度学习驱动的天然产品生物合成路径导航。
245.Cis- and trans-resveratrol have opposite effects on histone serine-ADP-ribosylation and tyrosine induced neurodegeneration.
顺式和反式白藜芦醇对组蛋白丝氨酸-ADP-核苷酸化和酪氨酸诱导的神经退行性有相反的影响。
246.Embryo-scale epithelial buckling forms a propagating furrow that initiates gastrulation.
胚胎规模的上皮屈曲形成了一个传播沟，启动了胃肠发育。
247.Evolution of sexual systems, sex chromosomes and sex-linked gene transcription in flatworms and roundworms.
扁形虫和蛔虫的性系统、性染色体和性连锁基因转录的进化。
248.Parallel ventral hippocampus-lateral septum pathways differentially regulate approach-avoidance conflict.
平行的腹侧海马-侧隔膜通路不同程度地调节接近-回避冲突。
249.Imaging translational control by Argonaute with single-molecule resolution in live cells.
在活细胞中以单分子分辨率对Argonaute的翻译控制进行成像。
250.Factors shaping the abundance and diversity of the gut archaeome across the animal kingdom.
塑造整个动物王国的肠道考古组的丰度和多样性的因素。
251.Excess ribosomal protein production unbalances translation in a model of Fragile X Syndrome.
过多的核糖体蛋白生产使脆性X综合征模型中的翻译失衡。
252.Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer.
FGFR抑制剂AZD4547治疗内分泌耐药乳腺癌的IIa期RADICAL试验结果。
253.Deep neural network trained on gigapixel images improves lymph node metastasis detection in clinical settings.
在千兆像素图像上训练的深度神经网络改善了临床上的淋巴结转移检测。
254.Microfluidics for understanding model organisms.
用于理解模型生物的微流控技术。
255.Airway Prevotella promote TLR2-dependent neutrophil activation and rapid clearance of Streptococcus pneumoniae from the lung.
气道普雷沃特菌促进TLR2依赖性中性粒细胞的激活和肺部肺炎链球菌的快速清除。
256.Controlling synthetic membraneless organelles by a red-light-dependent singlet oxygen-generating protein.
用一种依赖红光的单线态氧生成蛋白控制合成的无膜细胞器。
257.Structural Basis for pH-gating of the K+ channel TWIK1 at the selectivity filter.
K+通道TWIK1在选择性过滤器处的pH门控的结构基础。
258.Mechanically active integrins target lytic secretion at the immune synapse to facilitate cellular cytotoxicity.
机械活跃的整合素在免疫突触中以细胞分泌为目标，促进细胞毒性的产生。
259.Large-scale multi-omics analysis suggests specific roles for intragenic cohesin in transcriptional regulation.
大规模的多组学分析表明基因内协同蛋白在转录调控中的特定作用。
260.Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq data.
从单细胞RNA-Seq数据推断细胞-细胞通讯的方法和资源比较。
261.A single-cell transcriptomic atlas characterizes the silk-producing organ in the silkworm.
一个单细胞转录组图谱描述了家蚕产丝器官的特征。
262.Mitigation of SARS-CoV-2 transmission at a large public university.
缓解SARS-CoV-2在一所大型公立大学的传播。
263.Lactobacillus rhamnosus colonisation antagonizes Candida albicans by forcing metabolic adaptations that compromise pathogenicity.
鼠李糖乳杆菌定植通过迫使代谢适应性损害致病性来对抗白色念珠菌。
264.Efferocytosis requires periphagosomal Ca2+-signaling and TRPM7-mediated electrical activity.
吞噬作用需要吞噬体周围的Ca2+信号传导和TRPM7介导的电活动。
265.Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
观察正确和错误的核苷酸插入捕捉到隐藏的聚合酶保真度检查点。
266.SMYD5 catalyzes histone H3 lysine 36 trimethylation at promoters.
SMYD5催化启动子的组蛋白H3赖氨酸36三甲基化。
267.Drought-exposure history increases complementarity between plant species in response to a subsequent drought.
干旱暴露史增加了植物物种之间对后续干旱反应的互补性。
268.An in vitro model of neuronal ensembles.
一个体外的神经元集合体模型。
269.Physiological adaptive traits are a potential allele reservoir for maize genetic progress under challenging conditions.
生理适应性状是挑战性条件下玉米遗传进展的潜在等位基因库。
270.A Catharanthus roseus Fe(II)/α-ketoglutarate-dependent dioxygenase catalyzes a redox-neutral reaction responsible for vindolinine biosynthesis.
一种长春花的Fe(II)/α-酮戊二酸依赖性二氧酶催化氧化还原中性反应，负责藤本植物的生物合成。
271.Dynamic mRNA degradome analyses indicate a role of histone H3K4 trimethylation in association with meiosis-coupled mRNA decay in oocyte aging.
动态mRNA降解组分析表明组蛋白H3K4三甲基化在卵母细胞衰老过程中与减数分裂耦合的mRNA衰减有关的作用。
272.Norepinephrine potentiates and serotonin depresses visual cortical responses by transforming eligibility traces.
去甲肾上腺素通过转化资格痕迹增强和5-羟色胺抑制视觉皮质反应。
273.Transformation of dolutegravir into an ultra-long-acting parenteral prodrug formulation.
将多诺德格拉维转化为超长效肠外原药制剂。
274.Molecularly cleavable bioinks facilitate high-performance digital light processing-based bioprinting of functional volumetric soft tissues.
分子可裂解的生物墨水促进了高性能的基于数字光处理的功能性体积软组织的生物打印。
275.Evolutionary action of mutations reveals antimicrobial resistance genes in Escherichia coli.
突变的进化作用揭示了大肠杆菌的抗微生物基因。
276.Cerebellar stimulation prevents Levodopa-induced dyskinesia in mice and normalizes activity in a motor network.
小脑刺激可防止左旋多巴引起的小鼠运动障碍，并使运动网络的活动正常化。
277.Profiling Fusobacterium infection at high taxonomic resolution reveals lineage-specific correlations in colorectal cancer.
在高分类分辨率下对镰刀菌感染进行剖析，揭示了结直肠癌中的线粒体特异性关联。
278.Extracellular release of two peptidases dominates generation of the trypanosome quorum-sensing signal.
细胞外释放的两种肽酶主导了锥虫法定量感应信号的产生。
279.Waning effectiveness of the third dose of the BNT162b2 mRNA COVID-19 vaccine.
BNT162b2 mRNA COVID-19疫苗第三剂的有效性减弱。
280.Malaria oocysts require circumsporozoite protein to evade mosquito immunity.
疟疾卵囊需要环孢子虫蛋白来逃避蚊子的免疫。
281.Effectiveness of BBIBP-CorV vaccine against severe outcomes of COVID-19 in Abu Dhabi, United Arab Emirates.
阿拉伯联合酋长国阿布扎比BBIBP-CorV疫苗对COVID-19严重后果的有效性。
282.Structural basis of ligand binding modes of human EAAT2.
人类EAAT2配体结合模式的结构基础。
283.Longitudinal evidence that Event Related Potential measures of self-regulation do not predict everyday goal pursuit.
纵向证据表明，自我调控的事件相关电位测量不能预测日常目标的追求。
284.Association between resting-state functional brain connectivity and gene expression is altered in autism spectrum disorder.
自闭症谱系障碍中静止状态脑功能连接和基因表达之间的关联被改变。
285.Proteomic and functional analyses of the periodic membrane skeleton in neurons.
神经元中周期性膜骨架的蛋白质组学和功能分析。
286.Robust and accurate estimation of paralog-specific copy number for duplicated genes using whole-genome sequencing.
利用全基因组测序对重复基因的准系谱特异性拷贝数进行了稳健而准确的估计。
287.Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci.
不同形式的疝气的全面全基因组关联研究确定了80多个相关位点。
288.Disease-economy trade-offs under alternative epidemic control strategies.
替代流行病控制策略下的疾病-经济权衡。
289.Rapid, adaptable and sensitive Cas13-based COVID-19 diagnostics using ADESSO.
使用ADESSO进行快速、适应性强且敏感的基于Cas13的COVID-19诊断。
290.Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals.
计算识别感染者抗体重现中具有共同HCDR3二硫键图案的HCV中和抗体。
291.Genome-wide mapping of individual replication fork velocities using nanopore sequencing.
利用纳米孔测序技术绘制单个复制叉速度的全基因组图谱。
292.The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis.
EXTL3的结构有助于解释双域外植体蛋白在硫酸肝素合成中的不同作用。
293.Targeting parvalbumin promotes M2 macrophage polarization and energy expenditure in mice.
靶向小清蛋白促进小鼠M2巨噬细胞的极化和能量消耗。
294.Striatal hub of dynamic and stabilized prediction coding in forebrain networks for olfactory reinforcement learning.
前脑网络中嗅觉强化学习的动态和稳定的预测编码的纹状体枢纽。
295.RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.
RNF43 G659fs是一种致癌性结直肠癌突变，使肿瘤细胞对PI3K/mTOR抑制敏感。
296.Control of CRK-RAC1 activity by the miR-1/206/133 miRNA family is essential for neuromuscular junction function.
miR-1/206/133 miRNA家族对CRK-RAC1活性的控制对神经肌肉接头功能至关重要。
297.Ligand recognition and biased agonism of the D1 dopamine receptor.
D1多巴胺受体的配体识别和偏向激动作用。
298.Hippocampal representations switch from errors to predictions during acquisition of predictive associations.
海马表征在获得预测性关联过程中从错误到预测的转换。
299.Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.
人类极长链脂肪酸转运体ABCD1的底物识别和转运的结构基础。
300.Defining TCRγδ lymphoproliferative disorders by combined immunophenotypic and molecular evaluation.
通过联合免疫表型和分子评估定义TCRγδ淋巴增生性疾病.
301.Taf2 mediates DNA binding of Taf14.
Taf2介导Taf14的DNA结合。
302.Global relationships in tree functional traits.
树木功能性状的全球关系。
303.Short- and long-read metagenomics expand individualized structural variations in gut microbiomes.
短读和长读元基因组学拓展了肠道微生物组的个体化结构变化。
304.Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET.
白细胞衍生的趋化素2是一个通过原癌基因MET作用的抗病毒调节器。
305.Efficient aqueous remote loading of peptides in poly(lactic-co-glycolic acid).
聚(乳酸-co-glycolic acid)中多肽的高效水性远程装载。
306.Deep learning enables reference-free isotropic super-resolution for volumetric fluorescence microscopy.
深度学习实现了体积荧光显微镜的无参照物各向同性超分辨率。
307.Altered predictive control during memory suppression in PTSD.
PTSD记忆抑制过程中的预测控制改变.
308.Immune monitoring and treatment in immune-mediated inflammatory diseases.
免疫介导的炎症性疾病的免疫监测和治疗。
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