Question 问题：

Once a diagnosis of pulmonary embolism is made, prompt initiation of anticoagulation is imperative as it has been shown to reduced mortality. If necessary, what conservative efforts can be employed to reduce RV afterload? 

一旦肺梗塞诊断成立，尽快开始抗凝治疗是关键的，因为其可以降低死亡率。如需要，使用什么保守方法可以降低右室后负荷？

Answer 答案：

Conservative efforts to reduce RV afterload include oxygen supplementation and inhaled nitric oxide to assist with pulmonary vasodilation. For severe RV dysfunction, an inotropic agent such as dobutamine, should be initiated. 

降低后负荷的保守方法有给氧和吸入有助于肺血管扩张的一氧化氮。对于严重右室功能不全，应该开始给予一种正性肌力药，如多巴酚丁胺。

参考文献：

Crit Care. 2021;25:311