【热门产品推介】武汉佰乐博代理:Research Grade Labetuzumab
武汉佰乐博代理:Research Grade Labetuzumab
货号:DHC21001
产品链接:http://www.atagenix.com/product_detail-75486.html
产品购买联系方式:027-65279366
产品介绍:Labetuzumab是一种人源化抗癌胚抗原(CEA)单克隆抗体,可抑制肿瘤生长并使人类髓样甲状腺癌异种细胞对Dacarbazine化疗敏感。
通用名:Labetuzumab
纯度:>95% by SDS-PAGE.
浓度:1mg/ml
Formulationicon:0.01M PBS, pH 7.4.
内毒素:Please contact with the lab for this information.
别名:hMN14, IMMU-130, hMN-14-SN-38, hMN-14-SN-38 ADC, hMN14-CL-SN-38, Labetuzumab Govitecan
靶点;物种:Human CD66e/CEA/CEACAM5
种类:Humanized
受体鉴定:IgG1-kappa
CAS: 219649-07-7
存储条件:Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
参考文献:
Phase I/II Trial of Labetuzumab Govitecan (Anti-CEACAM5/SN-38 Antibody-Drug Conjugate) in Patients With Refractory or Relapsing Metastatic Colorectal Cancer. PMID: 28817371
Initial experience with high-dose radioimmunotherapy of metastatic medullary thyroid cancer using 131I-MN-14 F(ab)2 anti-carcinoembryonic antigen MAb and AHSCR. PMID: 10647610
Prospects of radioimmunotherapy in epithelial ovarian cancer: results with iodine-131-labeled murine and humanized MN-14 anti-carcinoembryonic antigen monoclonal antibodies. PMID: 9441773