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简要介绍|β-淀粉样蛋白(1-38)/β-Amyloid(1-38)|的相关信息

2022-11-23 17:02 作者:youngshe-Leslie  | 我要投稿

β-淀粉样蛋白是AD脑中淀粉样蛋白沉积的主要成分。β-淀粉样肽有一个异质的C末端,大多数由aβ1-40组成,而次要产物是aβ1-42。通常还会产生其他次要的aβ肽,如β-淀粉状肽1-34、1-37、1-38和1-39,很少有报告量化了这些肽在大脑中的水平。

Beta-amyloid  is the main component of amyloid deposits in the AD brain. Beta-amyloid  peptides have a heterogeneous C-terminus with the majority composed  ofAβ1-40, while a minor product is Aβ 1-42. Additional minor Aβ peptides  are also normally produced, such as Beta-amyloid 1-34, 1-37, 1-38 and  1-39, and few reports have quantified the levels of these peptides in  the brain.

以下是关于β-淀粉样蛋白(1-38)/β-Amyloid(1-38)的相关信息:

Sequence one letter code:

DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGG

Sequence three letter code:

H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-OH

CAS: 131438-74-9

Molecular Formula: C184H277N51O56S

Molecular Mass/ Weight: 4131.9


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