【标题速读】【nchem】【2023年】【5-8月】
声明：本专栏主要对生命科学领域的一些期刊文章标题进行翻译，所有内容均由本人手工整理翻译。由于本人专业为生物分析相关，其他领域如果出现翻译错误请谅解。
1.Dynamic chirality control. Stereogenic sp 3-hybridized carbon centres are the principal building blocks of chiral organic molecules. Usually, these centres are configurationally fixed. Now, a team led by Paul R. McGonigal has taken advantage of low-energy pericyclic rearrangements to create rigid cage molecules with fluxional sp 3 stereochemistry, influencing chiral information transfer. The sp 3-carbon stereochemistry of the cages is inverted through strain-assisted Cope rearrangements. The cover shows the fluxional carbon cage structure.
动态手性控制。立体异构sp 3 杂化碳中心是手性有机分子的主要构建模块。通常，这些中心的配置是固定的。现在，Paul R. McGonigal 领导的团队利用低能周环重排创造了具有流动 sp 3 立体化学的刚性笼分子，影响手性信息传递。笼的 sp 3-碳立体化学通过应变辅助 Cope 重排被反转。封面展示了流动的碳笼结构。
2.Control of dynamic sp3-C stereochemistry.
动态 sp3-C 立体化学的控制。
3.A columnar liquid quasicrystal with a honeycomb structure that consists of triangular, square and trapezoidal cells.
具有蜂窝结构的柱状液体准晶体，由三角形、正方形和梯形细胞组成。
4.Isolation, bonding and reactivity of a monomeric stibine oxide.
单体氧化锑的分离、键合和反应性。
5.Aromatic hexazine [N6]4− anion featured in the complex structure of the high-pressure potassium nitrogen compound K9N56.
高压钾氮化合物 K9N56 复杂结构中具有芳香族六嗪 [N6]4− 阴离子。
6.Modular enantioselective access to β-amino amides by Brønsted acid-catalysed multicomponent reactions.
通过布朗斯台德酸催化多组分反应模块化对映选择性获得 β-氨基酰胺。
7.Connecting the geometric and electronic structures of the nitrogenase iron–molybdenum cofactor through site-selective 57Fe labelling.
通过位点选择性 57Fe 标记连接固氮酶铁钼辅因子的几何结构和电子结构。
8.Stepwise on-demand functionalization of multihydrosilanes enabled by a hydrogen-atom-transfer photocatalyst based on eosin Y.
基于曙红 Y 的氢原子转移光催化剂实现多氢硅烷的逐步按需官能化。
9.Autonomous and directional flow of water and transport of particles across a subliming dynamic crystal surface.
水的自主定向流动和颗粒在升华动态晶体表面的传输。
10.Catalytic undirected borylation of tertiary C–H bonds in bicyclo[1.1.1]pentanes and bicyclo[2.1.1]hexanes.
双环[1.1.1]戊烷和双环[2.1.1]己烷中叔C-H键的催化无向硼基化。
11.Spatiotemporal functional assembly of split protein pairs through a light-activated SpyLigation.
通过光激活 SpyLigation 进行分裂蛋白对的时空功能组装。
12.Electrochemical synthesis of propylene from carbon dioxide on copper nanocrystals.
铜纳米晶体上二氧化碳电化学合成丙烯。
13.Catalytic enantioselective nucleophilic desymmetrization of phosphonate esters.
膦酸酯的催化对映选择性亲核去对称化。
14.Isolation of a californium(II) crown–ether complex.
锎(II)冠醚络合物的分离。
15.OregonFluor enables quantitative intracellular paired agent imaging to assess drug target availability in live cells and tissues.
OregonFluor 能够进行定量细胞内配对试剂成像，以评估活细胞和组织中药物靶标的可用性。
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1.Arene addition. 1,3-Dipolar cycloadditions are well known transformations in organic synthesis, however, the reactivity of benzene rings in these processes is underexplored. Now, a team led by Valery V. Fokin has shown that diazoalkenes — generated in situ from lithium acetylides and N-sulfonyl azides — can undergo intramolecular 1,3-dipolar cycloaddition with aromatic rings. The process provides a route for the synthesis of medicinally relevant heterocycles. The cover shows an artistic representation of an aromatic ring reacting with a diazoalkene.
添加芳烃。 1,3-偶极环加成是有机合成中众所周知的转化，然而，这些过程中苯环的反应性尚未得到充分研究。现在，由 Valery V. Fokin 领导的团队证明，由乙炔锂和 N-磺酰叠氮化物原位生成的重氮烯烃可以与芳香环进行分子内 1,3-偶极环加成。该方法为合成医学相关杂环化合物提供了一条途径。封面展示了芳环与重氮烯反应的艺术表现。
2.Not all catenanes with oriented rings are topologically chiral.
并非所有具有定向环的索烯都是拓扑手性的。
3.Arenes participate in 1,3-dipolar cycloaddition with in situ-generated diazoalkenes.
芳烃参与与原位生成的重氮烯烃的 1,3-偶极环加成反应。
4.A high-dimensional microfluidic approach for selection of aptamers with programmable binding affinities.
用于选择具有可编程结合亲和力的适体的高维微流体方法。
5.A catenane that is topologically achiral despite being composed of oriented rings.
尽管由定向环组成，但在拓扑上是非手性的索烯。
6.Indole-5,6-quinones display hallmark properties of eumelanin.
5,6-吲哚醌显示出真黑素的标志性特性。
7.Metal-free reduction of CO2 to formate using a photochemical organohydride-catalyst recycling strategy.
使用光化学有机氢化物催化剂回收策略将二氧化碳无金属还原为甲酸盐。
8.Spatiotemporal and global profiling of DNA–protein interactions enables discovery of low-affinity transcription factors.
DNA-蛋白质相互作用的时空和全局分析能够发现低亲和力转录因子。
9.Synthesis of planar chiral ferrocenes via enantioselective remote C–H activation.
通过对映选择性远程 C-H 活化合成平面手性二茂铁。
10.Uniform segmented platelet micelles with compositionally distinct and selectively degradable cores.
均匀分段的血小板胶束，具有成分不同且可选择性降解的核心。
11.Emulsion-oriented assembly for Janus double-spherical mesoporous nanoparticles as biological logic gates.
作为生物逻辑门的 Janus 双球形介孔纳米粒子的乳液导向组装。
12.Growth of single-crystal imine-linked covalent organic frameworks using amphiphilic amino-acid derivatives in water.
使用两亲性氨基酸衍生物在水中生长单晶亚胺连接的共价有机框架。
13.Accurate structure models and absolute configuration determination using dynamical effects in continuous-rotation 3D electron diffraction data.
利用连续旋转 3D 电子衍射数据中的动力学效应进行精确的结构模型和绝对构型确定。
14.Nature-inspired methylated polyhydroxybutyrates from C1 and C4 feedstocks.
来自 C1 和 C4 原料的受自然启发的甲基化聚羟基丁酸酯。
15.Regio- and enantioselective remote dioxygenation of internal alkenes.
内部烯烃的区域选择性和对映选择性远程双氧化。
16.A C–H activation-based enantioselective synthesis of lower carbo[n]helicenes.
基于 AC-H 活化的低碳[n]螺烯的对映选择性合成。
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1.Complex colloidal clathrate crystals. Clathrates, which consist of host molecules arranged in a hierarchy of polyhedral cages around guest species that they encapsulate, have attracted much attention for their host–guest chemistry. Now, using simulations, Sharon Glotzer and co-workers have shown that hard, otherwise non-interacting particles with truncated triangular bipyramid shapes self-assemble into open colloidal crystals isostructural to clathrates using only entropy. The resulting structures (depicted on the cover) consist of freely rotating guests within a rigid host network.
复杂的胶体包合物晶体。包合物由排列在其封装的客体物种周围的多面体笼层次结构中的主体分子组成，其主客体化学引起了广泛关注。现在，Sharon Glotzer 和同事通过模拟表明，具有截断三角双锥形状的坚硬的、非相互作用的粒子仅使用熵就可以自组装成与包合物同构的开放胶体晶体。由此产生的结构（如封面所示）由严格的主题网络内自由轮换的客体组成。
2.Route to complex colloidal crystals through entropy compartmentalization.
通过熵区室化形成复杂的胶体晶体。
3.Five mutually orthogonal aaRS–tRNA pairs for genetic code expansion.
用于遗传密码扩展的五个相互正交的 aaRS-tRNA 对。
4.Entropy compartmentalization stabilizes open host–guest colloidal clathrates.
熵区室化稳定了开放的主客体胶体包合物。
5.Atomistic simulations of the Escherichia coli ribosome provide selection criteria for translationally active substrates.
大肠杆菌核糖体的原子模拟为翻译活性底物提供了选择标准。
6.Multistep, site-selective noncovalent synthesis of two-dimensional block supramolecular polymers.
二维嵌段超分子聚合物的多步、位点选择性非共价合成。
7.Near-infrared-activated anticancer platinum(IV) complexes directly photooxidize biomolecules in an oxygen-independent manner.
近红外激活的抗癌铂（IV）络合物以不依赖于氧的方式直接光氧化生物分子。
8.Surface-exposed silver nanoclusters inside molecular metal oxide cavities.
分子金属氧化物空腔内表面暴露的银纳米簇。
9.Quintuply orthogonal pyrrolysyl-tRNA synthetase/tRNAPyl pairs.
五重正交吡咯赖氨酰-tRNA 合成酶/tRNAPyl 对。
10.Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-α-amino acids in vitro and in vivo.
扩大吡咯赖氨酰转移 RNA 合成酶的底物范围，包括体外和体内的非 α-氨基酸。
11.Real-time monitoring of reaction stereochemistry through single-molecule observations of chirality-induced spin selectivity.
通过手性诱导的自旋选择性的单分子观察实时监测反应立体化学。
12.In vivo metallophilic self-assembly of a light-activated anticancer drug.
光激活抗癌药物的体内亲金属自组装。
13.Multi-site programmable functionalization of alkenes via controllable alkene isomerization.
通过可控烯烃异构化对烯烃进行多位点可编程官能化。
14.In vitro selection of macrocyclic peptide inhibitors containing cyclic γ2,4-amino acids targeting the SARS-CoV-2 main protease.
体外选择含有针对 SARS-CoV-2 主要蛋白酶的环状 γ2,4-氨基酸的大环肽抑制剂。
15.Spin-dependent reactivity and spin-flipping dynamics in oxygen atom scattering from graphite.
石墨散射氧原子的自旋相关反应性和自旋翻转动力学。
16.Transient water wires mediate selective proton transport in designed channel proteins.
瞬态水线介导设计的通道蛋白中的选择性质子传输。
17.Why charging Li–air batteries with current low-voltage mediators is slow and singlet oxygen does not explain degradation.
为什么用当前的低压介体对锂空气电池充电速度很慢，并且单线态氧并不能解释降解。
18.Activity-based directed evolution of a membrane editor in mammalian cells.
哺乳动物细胞膜编辑器基于活动的定向进化。
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1.Copper-catalysed carbene chemistry. While the use of metal catalysts to control the reactivity of carbenes has long offered a powerful approach to organic synthesis, copper difluorocarbene chemistry has so far been elusive. Now, Xiao-Song Xue, Xingang Zhang and co-workers have synthesized and isolated copper(I) difluorocarbene complexes, which have enabled the development of a copper-catalysed difluorocarbene transfer reaction. The cover depicts an artistic representation of the copper(I) complex reacting with free difluorocarbene compounds.
铜催化卡宾化学。虽然使用金属催化剂来控制卡宾的反应性长期以来为有机合成提供了一种强大的方法，但二氟卡宾铜的化学迄今为止仍难以实现。现在，薛晓松、张新刚及其同事合成并分离了二氟卡宾铜(I)络合物，这使得铜催化的二氟卡宾转移反应得以发展。封面描绘了铜（I）配合物与游离二氟卡宾化合物反应的艺术表现。
2.A near-linear lanthanide complex that displays magnet-like behaviour.
一种近线性镧系元素络合物，表现出类似磁铁的行为。
3.Synthesis of oligosaccharide libraries for systematic explorations of heparan sulfate sequence space.
合成寡糖文库以系统探索硫酸乙酰肝素序列空间。
4.Copper-catalysed difluorocarbene transfer enables modular synthesis.
铜催化的二氟卡宾转移可实现模块化合成。
5.A bridged backbone strategy enables collective synthesis of strychnan alkaloids.
桥接骨架策略能够集体合成马钱子生物碱。
6.Tandem intermolecular [4 + 2] cycloadditions are catalysed by glycosylated enzymes for natural product biosynthesis.
串联分子间[4 + 2]环加成由糖基化酶催化，用于天然产物生物合成。
7.Energy-transfer-induced [3+2] cycloadditions of N–N pyridinium ylides.
N-N吡啶鎓叶立德的能量转移诱导的[3+2]环加成。
8.A trivalent 4f complex with two bis-silylamide ligands displaying slow magnetic relaxation.
具有两个双甲硅烷基酰胺配体的三价 4f 络合物，表现出缓慢的磁弛豫。
9.Efficient platform for synthesizing comprehensive heparan sulfate oligosaccharide libraries for decoding glycosaminoglycan–protein interactions.
用于合成综合硫酸乙酰肝素寡糖文库以解码糖胺聚糖-蛋白质相互作用的高效平台。
10.Exciton annihilation in molecular aggregates suppressed through quantum interference.
通过量子干涉抑制分子聚集体中的激子湮灭。
11.The dynamics of agonist-β2-adrenergic receptor activation induced by binding of GDP-bound Gs protein.
GDP 结合 Gs 蛋白结合诱导激动剂-β2-肾上腺素能受体激活的动力学。
12.Bismuth radical catalysis in the activation and coupling of redox-active electrophiles.
氧化还原活性亲电子试剂的活化和偶联中的铋自由基催化。
13.Fibril formation and ordering of disordered FUS LC driven by hydrophobic interactions.
由疏水相互作用驱动的无序 FUS LC 的原纤维形成和排序。
14.2-Oxabicyclo[2.1.1]hexanes as saturated bioisosteres of the ortho-substituted phenyl ring.
2-氧杂双环[2.1.1]己烷作为邻位取代苯环的饱和生物等排体。
15.Fragmentation and [4 + 3] cycloaddition in sodorifen biosynthesis.
sodorifen 生物合成中的断裂和 [4 + 3] 环加成。
16.Efficient photon upconversion enabled by strong coupling between silicon quantum dots and anthracene.
通过硅量子点和蒽之间的强耦合实现高效的光子上转换。
17.Tubulin engineering by semi-synthesis reveals that polyglutamylation directs detyrosination.
半合成微管蛋白工程揭示多聚谷氨酰化指导去酪氨酸化。
18.Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors.
金属依赖性酶对称性指导萜烯前体的生物合成通量。
