《急诊每日一题》神经氨酸酶抑制剂(NAI)对流感的作用2021年3月
Question 问题:
Neuraminidase inhibitors are commonly used in the treatment of influenza. NAI’s reduce the duration of symptoms by how long? What is their effect on hospitalization and adverse events (e.g. pneumonia) from influenza?
神经氨酸酶抑制剂(NAI)(如奥司他韦)常用于治疗流行性感冒。NAI会使症状缩短多长时间?这些药对因流感而住院或严重合并症(如肺炎)有什么影响?
Answer 答案:
Existing data indicate that NAIs reduce the duration of symptoms by < 1 day (14-17 hours) in adults with confirmed or suspected influenza. NAIs are not associated with reduction in hospitalization or disease complication.
现有数据显示NAIs使确诊或疑似流感成人症状缩短少于1天(14-17小时)。NAIs与减少住院或其合并症无关。
参考文献:
Acad EM, epub, 2/26/21