活性氧N-acetyl-L-Cysteine amide,CAS No. 38520-57-9
产品名称:活性氧N-acetyl-L-Cysteine amide,CAS No. 38520-57-9
产地:西安
规格:1mg 5mg 10mg
纯度:99%
用途:仅用于科研
状态:固体/粉末
储藏条件:冷藏-20℃
温馨提示:仅用于科研,不能用于人体实验!
说明:提供使用说明,核磁图谱,包装,价格,产地,制备方法,应用,稳定性,溶解度,简单合成等各种信息
N-acetyl-L-Cysteine amide (NACA) is an antioxidant.It is the amide form of N-acetyl-L-cysteine and has increased cellular membrane and blood-brain barrier permeability compared to NAC. NACA (750 μM) inhibits glutamate-induced cytotoxicity, decreases in intracellular glutathione (GSH) levels, and increases in intracellular reactive oxygen species (ROS) levels in PC12 cells.It reduces cortical tissue damage and decreases the distance traveled to the platform in the Morris water maze in a rat model of traumatic brain injury.NACA (60 and 120 mg/kg) also inhibits ovalbumin-induced decreases in GSH, increases in nuclear NF-κB p65 and HIF-1α, and increases in IL-4, IL-5, and IL-13 levels in mouse lung tissue.

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编辑:XAQYBIO HAO,2023年4月20日。

