CalBioreagents/艾美捷 ID蛋白单克隆抗体案例分析
CalBioreagents Id蛋白（Id=抑制DNA结合）是针对人类和小鼠Id1、Id2、Id3和Id4开发的一系列兔单克隆抗体。Id蛋白是转录的负性调节因子，Id1和Id3可能在血管生成中发挥中心作用。这些试剂适用于福尔马林固定的石蜡包埋组织的IHC和蛋白质印迹。一起来看下CalBioreagents/艾美捷 ID蛋白单克隆抗体相关案例分析：
CalBioreagents/艾美捷 ID蛋白单克隆抗体（cat#：M082）
蛋白质家族，Id1，Id2，Id3和Id4。这些蛋白质最初是作为蛋白质被发现的参与细胞的阴性控制区别Id蛋白起着阴性作用通过物理机制调节转录与一组转录因子的相互作用被称为bHLH（碱性螺旋-环-螺旋）蛋白质。Id蛋白与bHLH蛋白在细胞内相互作用阻止DNA与HLH结合的方式蛋白质。由于这项活动蛋白质被命名为Id（DNA抑制剂）绑定）。Id蛋白也被发现与与其他一些蛋白质如Rb，Ets，Paz、MIDA-1和SREBP-1c。Id蛋白可能在协调基因方面发挥中心作用表达、细胞增殖、肿瘤发生和血管生成。
Id蛋白被发现是在许多类型中过度表达，包括胶质母细胞瘤髓母细胞瘤神经母细胞瘤，胰腺癌、甲状腺癌、鳞状细胞癌细胞癌，乳腺癌，子宫内膜癌癌症、宫颈癌、黑色素瘤和网膜母细胞瘤。越来越多的人证据表明Id1和Id3在血管生成。Id1-/-，Id3中的实验-/-敲除小鼠表明，随着Id的丢失表达：无血管生成，无血管生成肿瘤的后续生长。
CalBioreagents/艾美捷 ID蛋白单克隆抗体相关研究：
ANALYTE TYPE DESCRIPTION APPLICATION PART # PKG
Id1 Rabbit Monoclonal Anti-Mouse Id1 Clone 37-2 WB, IHC M082 50 ug
Id1 Rabbit Monoclonal Anti-Mouse Id1 Clone 37-2 WB, IHC M083 100 ug
Id1 Rabbit Monoclonal Anti-Mouse Id1 Clone 37-2 WB, IHC M084 1 mg
Id1 Rabbit Monoclonal Anti-Human/Mouse Id1 Clone 195-14 WB, IHC M085 50 ug
Id1 Rabbit Monoclonal Anti-Human/Mouse Id1 Clone 195-14 WB, IHC M086 100 ug
Id1 Rabbit Monoclonal Anti-Human/Mouse Id1 Clone 195-14 WB, IHC M087 1 mg
Id1 Rabbit Monoclonal Anti-Human Id1 Clone 5-3 WB M088 50 ug
Id1 Rabbit Monoclonal Anti-Human Id1 Clone 5-3 WB M089 100 ug
Id1 Rabbit Monoclonal Anti-Human Id1 Clone 5-3 WB M090 1 mg
Id2 Rabbit Monoclonal Anti Human/Mouse Id2 Clone 9-2-8 WB, IHC M213 50 ug
Id2 Rabbit Monoclonal Anti Human/Mouse Id2 Clone 9-2-8 WB, IHC M214 100 ug
Id2 Rabbit Monoclonal Anti Human/Mouse Id2 Clone 9-2-8 WB, IHC M215 1 mg
Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 6-1 WB M094 50 ug
Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 6-1 WB M095 100 ug
Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 6-1 WB M096 1 mg
Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 16-1 WB M097 50 ug
Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 16-1 WB M098 100 ug
Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 16-1 WB M099 1 mg
Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 17-3 WB, IHC (IHC for Human only) M100 50 ug
Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 17-3 WB, IHC (IHC for Human only) M101 100 ug
Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 17-3 WB, IHC (IHC for Human only) M102 1 mg
Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 42-1 WB M103 50 ug
Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 42-1 WB M104 100 ug
Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 42-1 WB M105 1 mg
Id4 Rabbit Monoclonal Anti-Human/Mouse Id4 Clone 82-12 WB, IHC M106 50 ug
Id4 Rabbit Monoclonal Anti-Human/Mouse Id4 Clone 82-12 WB, IHC M107 100 mg
Id4 Rabbit Monoclonal Anti-Human/Mouse Id4 Clone 82-12 WB, IHC M108 1 mg
艾美捷科技是CalBioreagents的中国代理商，为科研工作者提供优质的产品与服务。
