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Ranibizumab (anti-VEGF)

品牌：MedChemExpress (MCE)

Drug_Names：Ranibizumab (anti-VEGF)

CAS：347396-82-1

产品活性：Ranibizumab (RG-6321) (anti-VEGF) 是一种人源化的抗 VEGF 单克隆抗体片段，能够识别所有 VEGF-A 亚型 (VEGF110，VEGF121，以及 VEGF165)。动物模型中，Ranibizumab (anti-VEGF) 减缓视力丧失，并用于老年黄斑变性 (AMD) 的研究。

存储条件：Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献：

Mustafa Şahiner, et al. The Effects of Anti-Vascular Endothelial Growth Factor Drugs on Retinal Pigment Epithelial Cell Culture. Turk J Ophthalmol. 2018 Aug;48(4):190-195.

K J Kim, et al. The vascular endothelial growth factor proteins: identification of biologically relevant regions by neutralizing monoclonal antibodies. Growth Factors. 1992;7(1):53-64.

Richard Filek, et al. Safety of anti-VEGF treatments in a diabetic rat model and retinal cell culture. Clin Ophthalmol. 2019 Jul 1;13:1097-1114.