【标题速读】【JACS】【2022年】【3月】

2023-06-05 16:59 作者:Rt_Cola 0人读过 | 我要投稿

声明：本专栏主要对生命科学领域的一些期刊文章标题进行翻译，所有内容均由本人手工整理翻译。由于本人专业为生物分析相关，其他领域如果出现翻译错误请谅解。

A new concise strategy is proposed for photosensitizer design based on pentamethine cyanine dye (Cy5). It provides an alternative meso-substituent group on Cy5 to transform as ER-targeting photosensitizer from a fluorescence probe, which will induce the ER stress and immunogenic cell death under near-infrared light irradiation.

提出了一种基于五次甲基花青染料 (Cy5) 的光敏剂设计新简洁策略。它在 Cy5 上提供了一个替代的中间取代基，从荧光探针转化为 ER 靶向光敏剂，这将在近红外光照射下诱导 ER 应激和免疫原性细胞死亡。

A peroxynitrite and pH dual-responsive near-infrared afterglow luminescent nanoprobe is designed and prepared for revealing the development process of acute inflammation, discrimination between inflammation and allergy, and screening of antitumor drugs capable of inducing immunogenic cell death.

设计制备了一种过氧亚硝酸盐和pH值双响应的近红外余辉发光纳米探针，用于揭示急性炎症的发展过程、炎症与过敏的鉴别以及诱导免疫原性细胞死亡的抗肿瘤药物的筛选。

A thorium-based nanocluster, Th-101, displaying extremely rare fluorochromic and piezochromic behaviors, as well as unprecedented radioresistance, has been developed. Further fabricating Th-101 into a custom-built optoelectronic device allows for colorimetric dosimetry of ionizing radiation based on a RGB concept.

已开发出一种钍基纳米团簇 Th-101，它显示出极为罕见的荧光变色和压电变色行为，以及前所未有的抗辐射性。进一步将 Th-101 制造成定制的光电设备，可以基于 RGB 概念进行电离辐射的比色剂量测定。

Inspired by the conformation-dependent mechanoresponse demonstrated in a piezo protein, a simple but powerful approach exploits the “guest molecule-mediation effect” to engineer a peptide MOF for a piezoelectric energy harvester. We show how the host–guest interaction has a dramatic effect on the electromechanical properties of the peptide MOF, providing another tool for modulating piezoelectricity in peptide-based nanotechnology.

受压电蛋白中显示的构象依赖性机械反应的启发，一种简单但有效的方法利用“客体分子介导效应”为压电能量收集器设计肽 MOF。我们展示了主客体相互作用如何对肽 MOF 的机电特性产生显着影响，为在基于肽的纳米技术中调节压电提供了另一种工具。

With facile activation of several C–H bonds in cyclohexane and desorption of benzene product, the fully exposed few-atom Pt ensembles with average Pt–Pt coordination number of 2–3 boost the optimized activity of cyclohexane dehydrogenation, whereas Pt single atoms have little activity and Pt large nanoparticles show much decreased activity.

随着环己烷中几个 C-H 键的容易活化和苯产物的解吸，完全暴露的 Pt 系综平均 Pt-Pt 配位数为 2-3 提高了环己烷脱氢的优化活性，而 Pt 单原子几乎没有活性和 Pt 大纳米颗粒显示出大大降低的活性。

A novel microporous metal–organic framework incorporating both a primary building unit and a hexanuclear secondary building unit has been developed. It exhibits optimal channels for splitting alkane isomers as a function of degrees of branching.

已经开发出一种结合了初级结构单元和六核二级结构单元的新型微孔金属有机框架。它展示了分裂烷烃异构体的最佳通道，作为支化度的函数。

H-FluNox, a new fluorescent probe for heme, reacts with labile heme in living cells.

H-FluNox 是一种新型血红素荧光探针，可与活细胞中不稳定的血红素发生反应。

Synthetic high-valent heme-oxo intermediates are utilized to mimic the indole monooxygenation functionality of heme enzymes. They mediate the facile conversion of a broad variety of indole motifs exclusively leading to corresponding 2-oxindoles in good to excellent yields. While shining light on crucial, yet unknown bio-relevant subtleties that are implicated in human pathogenesis, these systems hold promise as highly efficient, sustainable next generation catalysts for the production of oxindole pharmacophores.

合成的高价血红素氧代中间体用于模拟血红素酶的吲哚单氧化功能。它们介导了多种吲哚基序的轻松转化，专门导致相应的 2-oxindoles 具有良好到极好的收率。在阐明与人类发病机制有关的关键但未知的生物相关微妙之处的同时，这些系统有望成为用于生产羟吲哚药效团的高效、可持续的下一代催化剂。

Powered by electrical energy, a multienzyme bioelectrocatalytic system was constructed and successfully utilized to realize the challenging one-pot conversion from chemically inert hydrocarbons to imines, which would provide a new methodology for the comprehensive conversion and utilization of inert hydrocarbons.

以电能为动力，构建并成功利用多酶生物电催化系统，实现了具有挑战性的化学惰性碳氢化合物一锅法转化为亚胺，为惰性碳氢化合物的综合转化利用提供了一种新方法。

As a typical green bio-manufacturing technology, the enzyme-photo-coupled catalytic system (EPCSs) combines the natural enzyme with a library of semiconductor photocatalysts, holding great promise in clean energy conversion and bulk chemical synthesis. However, the efficiency of EPCSs strongly relies on the shuttling of energy-carrying molecules, e.g., NAD+/NADH cofactor, between active centers of the enzyme and the photocatalyst. Herein, the authors propose a strategy of constructing a thylakoid membrane-inspired capsule with fortified NAD+/NADH shuttling to boost the enzyme-photo-coupled catalytic process.

作为典型的绿色生物制造技术，酶光耦合催化系统（EPCSs）将天然酶与半导体光催化剂库相结合，在清洁能源转换和大宗化学合成方面具有广阔前景。然而，EPCS 的效率强烈依赖于携带能量的分子（例如 NAD+/NADH 辅助因子）在酶活性中心和光催化剂之间的穿梭。在此，作者提出了一种策略，即构建具有强化 NAD+/NADH 穿梭的类囊体膜胶囊，以促进酶光耦合催化过程。

A ubiquitous glycosyltransferase is transiently inactivated by a photocaged group, which is released upon UV irradiation to restore the enzyme activity in cells with spatiotemporal resolution.

一种普遍存在的糖基转移酶被光笼基团瞬时灭活，光笼基团在紫外线照射下释放，以恢复具有时空分辨率的细胞中的酶活性。

Understanding and regulating the cleavage of the O–O bond in oxidants is key to the development of new Fe-based catalytic oxidation systems. Based on the flexible FeOCl scaffold, a new K+-intercalated FeOCl catalyst is designed to steer the H2O2 activation pathway from a traditional Fenton-like pathway on FeOCl to a nonradical ferryl (Fe(IV)=O) pathway, exhibiting the efficient coupling reactivity for the removal of various organic pollutants.

理解和调节氧化剂中 O-O 键的断裂是开发新型铁基催化氧化系统的关键。基于灵活的 FeOCl 支架，设计了一种新的 K+ 插层 FeOCl 催化剂，将 H2O2 活化途径从传统的 FeOCl 类芬顿途径转向非自由基铁基 (Fe(IV)=O) 途径，表现出高效的偶联反应性用于去除各种有机污染物。

Hydrogen bonds play an important role in the control of disulfide stereochemistry and enable stereodivergent chirality transfer in a series of 1,2-dithiolanes. In solutions, S–S•••H–N bonds are experimentally observed and thermodynamically quantified, enabling the intramolecular chirality transfer from amino acids to disulfide bonds. In the solid state, the formation of C=O•••H–N bonds results in single-crystalline helical assemblies. Image created by Qi Zhang.

氢键在控制二硫化物立体化学方面起着重要作用，并使一系列 1,2-二硫杂环戊烷中的立体发散手性转移成为可能。在溶液中，S–S•••H–N 键通过实验观察和热力学量化，使分子内手性从氨基酸转移到二硫键。在固态下，C=O•••H–N 键的形成导致单晶螺旋组件。图片由 Qi Zhang 创建。

Tuning of metal oxidation states in metal–organic framework (MOF) nodes through photoisomerization of organic linkers was probed for the first time. Photoswitch-imposed alternation between oxidation states of copper nodes was confirmed by comprehensive spectroscopic analysis. “On-demand” tunable properties could significantly advance framework development, resulting in material landscape expansion.

首次探讨了通过有机接头的光异构化来调节金属有机骨架 (MOF) 节点中的金属氧化态。通过综合光谱分析证实了光开关在铜节点氧化态之间的交替。 “按需”可调属性可以显着推进框架开发，从而导致材料景观扩展。

NOx Waste, Waste Not! A pincer-type Ni complex promotes catalytic deoxygenation of nitrogen oxyanions (NOx) and ultimately transfers a Ni-bound nitroso group to organic electrophiles, such as benzyl/alkyl halides, resulting in economically meaningful oxime products.

NOx 废物，不浪费！钳型 Ni 络合物促进氮氧阴离子 (NOx) 的催化脱氧，并最终将 Ni 结合的亚硝基转移到有机亲电子试剂，例如苄基/烷基卤化物，从而产生具有经济意义的肟产品。

Two nonplanar 2D covalent organic frameworks (COFs) with a square (c-HBC-COF) or kagome (DHP-COF) lattice are designed and synthesized from D2- and C4v-symmetric distorted aromatics with different π-conjugated structure. c-HBC-COF with more efficient π-stacking and large π-conjugation exhibits a photoconductivity and charge carrier mobility (up to 44 cm2 V–1 s–1) substantially higher than that of DHP-COF, as demonstrated by the terahertz spectroscopy.

由具有不同 π 共轭结构的 D2 和 C4v 对称畸变芳烃设计并合成了两种具有正方形 (c-HBC-COF) 或 kagome (DHP-COF) 晶格的非平面二维共价有机框架 (COF)。具有更有效的 π 堆叠和大 π 共轭的 c-HBC-COF 表现出远高于 DHP-COF 的光电导率和电荷载流子迁移率（高达 44 cm2 V–1 s–1），如太赫兹光谱所示 .

A linker compensation strategy is proposed to graft a S-containing group onto zeolitic imidazolate frameworks (S-CFZ), which is discovered to induce electron delocalization at Co active sites and enable satisfactory OH* adsorption/desorption energies for balanced OER/ORR performance. Consequently, the S-CFZ cathode delivers encouraging performance in practical rechargeable Zn–air batteries.

提出了一种接头补偿策略，将含 S 基团接枝到沸石咪唑酯骨架 (S-CFZ) 上，发现它可以在 Co 活性位点诱导电子离域，并实现令人满意的 OH* 吸附/解吸能量，以实现平衡的 OER/ORR 性能。因此，S-CFZ 阴极在实用的可充电锌空气电池中具有令人鼓舞的性能。

A copper/catechol-based metal-organic framework (CuHPT) was designed. It effectively disrupted dynamically balanced cellular redox homeostasis by consuming antioxidant glutathione (GSH) to help generate toxic radical oxidative species (ROS), thus selectively killing drug-resistant cancer cells, as they often had the high amount of GSH.

设计了铜/儿茶酚基金属有机框架 (CuHPT)。它通过消耗抗氧化剂谷胱甘肽 (GSH) 来帮助产生有毒的自由基氧化物质 (ROS)，从而有效地破坏动态平衡的细胞氧化还原稳态，从而选择性地杀死耐药癌细胞，因为它们通常含有大量的 GSH。

Achiral nanomaterials that crystallize in achiral point groups are generally optically inactive. Here, we report the surprising observation of optical activity in several achiral point groups for supercrystals assembled from anisotropic metal nanoclusters with atomic precision. Our findings have broadened the fundamental principles for producing nanomaterial-based optical activity and devices with polarization effects.

在非手性点群中结晶的非手性纳米材料通常不具有光学活性。在这里，我们报告了对由具有原子精度的各向异性金属纳米团簇组装而成的超晶在几个非手性点群中的光学活性的惊人观察。我们的研究结果拓宽了生产基于纳米材料的光学活性和具有偏振效应的设备的基本原理。

A lithium superionic conductor, phosphorous-substituted Li2SiS3, with a new framework structure consisting of isolated edge-sharing tetrahedral dimers is reported. It exhibits an anomalously high ionic conductivity, 3 orders of magnitude higher than the reported ionic conductivity for its polymorph formed by infinite corner-shared tetrahedral chains.

报道了一种锂超离子导体，磷取代的 Li2SiS3，具有由孤立的共享边缘四面体二聚体组成的新框架结构。它表现出异常高的离子电导率，比报告的由无限共角四面体链形成的多晶型物的离子电导率高 3 个数量级。

Two functional heterojunctions, Pd/NC and MoC/NC, are integrated together to construct unique mass (reactants and intermediates) exchange paths with interface charge-density-dependent transfer efficiencies, successfully triggering the capture and activation of CO2 and H2 molecules for mild and cascade methylation of amines.

两个功能性异质结 Pd/NC 和 MoC/NC 集成在一起，构建了独特的质量（反应物和中间体）交换路径，具有依赖于界面电荷密度的转移效率，成功地触发了 CO2 和 H2 分子的捕获和活化，用于温和和胺的级联甲基化。

A catalytic architecture comprising mesoporous silica shell surrounding platinum nanoparticles (green balls) supported on a solid silica sphere. During polyethylene (long red thread) hydrogenolysis, a polymer chain enters a pore, contacts a Pt nanoparticle where C–C bond cleavage occurs, and then smaller fragments (short red thread) exit the pore.

一种催化结构，包含围绕在固体二氧化硅球体上的铂纳米粒子（绿球）的介孔二氧化硅壳。在聚乙烯（长红线）氢解过程中，聚合物链进入孔隙，与 Pt 纳米颗粒接触并发生 C-C 键断裂，然后较小的片段（短红线）离开孔隙。

The spatial organization of molecules is a prerequisite for the complexity of biological systems. Inspired by this concept, chemists synthesize artificial capsules and cages that enable various levels of an organization. Here, we report a new interaction mode of well-known polyphenolic macrocycles with tetraalkylammonium salts that involves anions as crucial interacting partners and leads to the formation of anion-sealed capsular species.

分子的空间组织是生物系统复杂性的先决条件。受此概念的启发，化学家们合成了人造胶囊和笼子，以支持组织的各个层次。在这里，我们报告了一种众所周知的多酚大环化合物与四烷基铵盐的新相互作用模式，其中阴离子作为重要的相互作用伙伴，并导致形成阴离子密封的荚膜物质。

Elaborated hydrazines and hydrazine fragments can selectively inhibit the functions of proteins that possess electrophilic reactivity inside the cell.

精心制作的肼和肼片段可以选择性地抑制细胞内具有亲电反应性的蛋白质的功能。

A machinery nanosystem mimicking proteins' conformational change was developed. The nanosystem's folding/unfolding molecular motion response to the cellular environment enables the direct penetration of the systems across the cellular membrane to disrupt intracellular organelles. Also, the molecular pH-responsive switches were integrated into the system, inducing the selective apoptosis of cancer cells.

开发了一种模仿蛋白质构象变化的机械纳米系统。纳米系统对细胞环境的折叠/展开分子运动响应使系统能够直接穿透细胞膜以破坏细胞内细胞器。此外，分子 pH 响应开关被集成到系统中，诱导癌细胞的选择性凋亡。

1.Bulk Superlattice Analogues for Energy Conversion.

用于能量转换的体相超晶格类似物。

2.Chemical Evolution of Natural Product Structure.

天然产物结构的化学演化。

3.Nanoparticle Assembly as a Materials Development Tool.

纳米粒子组装作为材料开发工具。

4.Destabilized Carbocations Caged in Water Microdroplets: Isolation and Real-Time Detection of α-Carbonyl Cation Intermediates.

笼在水微滴中的不稳定碳正离子：α-羰基阳离子中间体的分离和实时检测。

5.Excited-State Palladium-Catalyzed Radical Migratory Mizoroki–Heck Reaction Enables C2-Alkenylation of Carbohydrates.

激发态钯催化的自由基迁移 Mizoroki–Heck 反应可实现碳水化合物的 C2-烯基化。

6.Histone H2B Deacylation Selectivity: Exploring Chromatin’s Dark Matter with an Engineered Sortase.

组蛋白 H2B 脱酰选择性：使用工程分选酶探索染色质的暗物质。

7.Noble-Metal High-Entropy-Alloy Nanoparticles: Atomic-Level Insight into the Electronic Structure.

贵金属高熵合金纳米粒子：电子结构的原子级洞察。

8.Bis-periazulene (Cyclohepta[def]fluorene) as a Nonalternant Isomer of Pyrene: Synthesis and Characterization of Its Triaryl Derivatives.

Bis-periazulene (Cyclohepta[def]fluorene) 作为芘的非交替异构体：其三芳基衍生物的合成与表征。

9.Evidence for Borylene Carbonyl (LHB═C═O) and Base-Stabilized (LHB═O) and Base-Free Oxoborane (RB≡O) Intermediates in the Reactions of Diborenes with CO2.

硼烯羰基 (LHB=C=O) 和碱稳定 (LHB=O) 和无碱氧代硼烷 (RB≡O) 中间体在二硼烯与 CO2 反应中的证据。

10.Broken-Symmetry Density Functional Theory Analysis of the Ω Intermediate in Radical S-Adenosyl-l-methionine Enzymes: Evidence for a Near-Attack Conformer over an Organometallic Species.

自由基 S-腺苷-l-甲硫氨酸酶中 Ω 中间体的破对称密度泛函理论分析：有机金属物种近攻构象的证据。

11.Engineering Lattice Disorder on a Photocatalyst: Photochromic BiOBr Nanosheets Enhance Activation of Aromatic C–H Bonds via Water Oxidation.

光催化剂上的工程晶格紊乱：光致变色 BiOBr 纳米片通过水氧化增强芳香 C-H 键的活化。

12.Conformational Gap Control in CsTaS3.

CsTaS3 中的构象间隙控制。

13.Trilayer Metal–Organic Frameworks as Multifunctional Electrocatalysts for Energy Conversion and Storage Applications.

三层金属有机框架作为能量转换和存储应用的多功能电催化剂。

14.Amplification of Activated Near-Infrared Afterglow Luminescence by Introducing Twisted Molecular Geometry for Understanding Neutrophil-Involved Diseases.

通过引入扭曲分子几何来放大激活的近红外余辉发光以了解中性粒细胞相关疾病。

15.Unveiling the Cation Exchange Reaction between the NASICON Li1.5Al0.5Ge1.5(PO4)3 Solid Electrolyte and the pyr13TFSI Ionic Liquid.

揭示 NASICON Li1.5Al0.5Ge1.5(PO4)3 固体电解质与 pyr13TFSI 离子液体之间的阳离子交换反应。

16.A New Concept of Radiation Detection Based on a Fluorochromic and Piezochromic Nanocluster.

基于荧光变色和压致变色纳米团簇的辐射检测新概念。

17.Highly Stable Neutral Corrole Radical: Amphoteric Aromatic–Antiaromatic Switching and Efficient Photothermal Conversion.

高度稳定的中性咔咯自由基：两性芳香-抗芳香转换和高效光热转换。

18.Guest Molecule-Mediated Energy Harvesting in a Conformationally Sensitive Peptide–Metal Organic Framework.

构象敏感肽-金属有机骨架中客体分子介导的能量收集。

19.ER-Targeting Cyanine Dye as an NIR Photoinducer to Efficiently Trigger Photoimmunogenic Cancer Cell Death.

ER 靶向花青染料作为 NIR 光诱导剂可有效触发光免疫原性癌细胞死亡。

20.Site-Specific Synthesis of N4-Acetylcytidine in RNA Reveals Physiological Duplex Stabilization.

RNA 中 N4-乙酰胞苷的位点特异性合成揭示了生理双链体稳定性。

21.H-Bonded Counterion-Directed Enantioselective Au(I) Catalysis.

氢键抗衡离子导向的对映选择性 Au(I) 催化。

22.Spontaneous Reduction-Induced Degradation of Viologen Compounds in Water Microdroplets and Its Inhibition by Host–Guest Complexation.

水微滴中紫精化合物的自发还原诱导降解及其通过主客体络合的抑制作用。

23.In Situ Investigation of Ultrafast Dynamics of Hot Electron-Driven Photocatalysis in Plasmon-Resonant Grating Structures.

等离子共振光栅结构中热电子驱动光催化超快动力学的原位研究。

24.Engineering Long-Lived Blue Photoluminescence from InP Quantum Dots Using Isomers of Naphthoic Acid.

使用萘甲酸的异构体从 InP 量子点设计长寿命蓝色光致发光。

25.Few-Atom Pt Ensembles Enable Efficient Catalytic Cyclohexane Dehydrogenation for Hydrogen Production.

少原子 Pt 系综可实现高效的催化环己烷脱氢制氢。

26.Photoactuating Artificial Muscles of Motor Amphiphiles as an Extracellular Matrix Mimetic Scaffold for Mesenchymal Stem Cells.

运动两亲动物的光驱动人工肌肉作为间充质干细胞的细胞外基质模拟支架。

27.Modulating Chemical Environments of Metal–Organic Framework-Supported Molybdenum(VI) Catalysts for Insights into the Structure–Activity Relationship in Cyclohexene Epoxidation.

调节金属-有机骨架负载的钼 (VI) 催化剂的化学环境，以深入了解环己烯环氧化中的结构-活性关系。

28.Stable and Functionally Diverse Versatile Peroxidases Designed Directly from Sequences.

直接根据序列设计的稳定且功能多样的多功能过氧化物酶。

29.Fluorescence Quenching by Redox Molecular Pumping.

通过氧化还原分子泵浦进行的荧光淬灭。

30.Set of Cytochrome P450s Cooperatively Catalyzes the Synthesis of a Highly Oxidized and Rearranged Diterpene-Class Sordarinane Architecture.

一组细胞色素 P450 协同催化高度氧化和重排的二萜类 Sordarinane 结构的合成。

31.Rational Design of 3d Transition-Metal Compounds for Thermoelectric Properties by Using Periodic Trends in Electron-Correlation Modulation.

利用电子相关调制的周期趋势合理设计 3d 过渡金属化合物的热电性能。

32.Hybridization from Guest–Host Interactions Reduces the Thermal Conductivity of Metal–Organic Frameworks.

宾主相互作用的杂交降低了金属有机框架的热导率。

33.A Bidirectional Bioinspired [FeFe]-Hydrogenase Model.

双向仿生 [FeFe]-氢化酶模型。

34.Rhodium-Based Metal–Organic Polyhedra Assemblies for Selective CO2 Photoreduction.

用于选择性 CO2 光还原的铑基金属-有机多面体组件。

35.Two-Component Redox Organocatalyst for Peptide Bond Formation.

用于肽键形成的双组分氧化还原有机催化剂。

36.A Strategy to Select Macrocyclic Peptides Featuring Asymmetric Molecular Scaffolds as Cyclization Units by Phage Display.

通过噬菌体展示选择具有不对称分子支架的大环肽作为环化单元的策略。

37.Synthesis of Vinylene-Linked Covalent Organic Frameworks by Monomer Self-Catalyzed Activation of Knoevenagel Condensation.

通过 Knoevenagel 缩合的单体自催化活化合成亚乙烯基连接的共价有机骨架。

38.Two-Dimensional Violet Phosphorus: A p-Type Semiconductor for (Opto)electronics.

二维紫磷：用于（光）电子学的 p 型半导体。

39.On the Origin of Rh-Catalyzed Selective Ring-Opening Amidation of Substituted Cyclopropanols to Access β2-Amino Ketones.

关于 Rh 催化取代环丙醇选择性开环酰胺化获得 β2-氨基酮的起源。

40.A Chiral Iron Disulfonate Catalyst for the Enantioselective Synthesis of 2-Amino-2′-hydroxy-1,1′-binaphthyls (NOBINs).

用于对映选择性合成 2-Amino-2'-hydroxy-1,1'-binaphthyls (NOBINs) 的手性二磺酸铁催化剂。

41.Electrochemical Dearomative Dicarboxylation of Heterocycles with Highly Negative Reduction Potentials.

具有高负还原电位的杂环的电化学脱芳双羧基化。

42.Rapid Inhibitor Discovery by Exploiting Synthetic Lethality.

通过利用合成杀伤力快速发现抑制剂。

43.Approaching the Spin-Statistical Limit in Visible-to-Ultraviolet Photon Upconversion.

接近可见光到紫外光子上转换中的自旋统计极限。

44.Impact of Molecular Design on Degradation Lifetimes of Degradable Imine-Based Semiconducting Polymers.

分子设计对可降解亚胺基半导体聚合物降解寿命的影响。

45.General Strategy for the Synthesis of Rare Sugars via Ru(II)-Catalyzed and Boron-Mediated Selective Epimerization of 1,2-trans-Diols to 1,2-cis-Diols.

通过 Ru(II) 催化和硼介导的 1,2-反式二醇选择性差向异构化为 1,2-顺式二醇合成稀有糖的一般策略。

46.Creating Optimal Pockets in a Clathrochelate-Based Metal–Organic Framework for Gas Adsorption and Separation: Experimental and Computational Studies.

在基于笼形螯合物的金属有机框架中创建用于气体吸附和分离的最佳口袋：实验和计算研究。

47.ATP-Responsive Liposomes via Screening of Lipid Switches Designed to Undergo Conformational Changes upon Binding Phosphorylated Metabolites.

通过筛选旨在在结合磷酸化代谢物时发生构象变化的脂质开关来获得 ATP 响应性脂质体。

48.An Engineered Cytidine Deaminase for Biocatalytic Production of a Key Intermediate of the Covid-19 Antiviral Molnupiravir.

一种用于生物催化生产 Covid-19 抗病毒药物 Molnupiravir 关键中间体的工程化胞苷脱氨酶。

49.A Microporous Metal–Organic Framework Incorporating Both Primary and Secondary Building Units for Splitting Alkane Isomers.

一种微孔金属-有机框架，结合了用于分解烷烃异构体的主要和次要构建单元。

50.Phototriggered Apoptotic Cell Death (PTA) Using the Light-Driven Outward Proton Pump Rhodopsin Archaerhodopsin-3.

使用光驱动外向质子泵视紫红质 Archaerhodopsin-3 的光触发细胞凋亡 (PTA)。

51.Switchable Regioselective 6-endo or 5-exo Radical Cyclization via Photoredox Catalysis.

通过 Photoredox 催化可切换区域选择性 6-内或 5-外自由基环化。

52.Quantum Dots Photocatalyze Intermolecular [2 + 2] Cycloadditions of Aromatic Alkenes Adsorbed to their Surfaces via van der Waals Interactions.

量子点光催化分子间 [2 + 2] 芳香烯烃通过范德瓦尔斯相互作用吸附到其表面的环加成。

53.Ligand Modification of Au25 Nanoclusters for Near-Infrared Photocatalytic Oxidative Functionalization.

用于近红外光催化氧化功能化的 Au25 纳米团簇的配体修饰。

54.Molecular Imaging of Labile Heme in Living Cells Using a Small Molecule Fluorescent Probe.

使用小分子荧光探针对活细胞中不稳定的血红素进行分子成像。

55.Distortion of the [FeNO]2 Core in Flavodiiron Nitric Oxide Reductase Models Inhibits N–N Bond Formation and Promotes Formation of Unusual Dinitrosyl Iron Complexes: Implications for Catalysis and Reactivity.

Flavodiiron 一氧化氮还原酶模型中 [FeNO]2 核的变形抑制 N-N 键形成并促进异常二亚硝基铁络合物的形成：对催化和反应性的影响。