Mepolizumab | 196078-29-2 - MedChemExpress
2023-02-24 15:35 作者:bili_92778524386 | 我要投稿
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Mepolizumab
品牌:MedChemExpress (MCE)
Drug_Names:Mepolizumab
CAS:196078-29-2
产品活性:Mepolizumab (SB 240563) 是一种人源化的单克隆抗体,可结合并中和白细胞介素 5 (IL-5),白细胞介素 5 (IL-5) 是参与嗜酸性粒细胞增殖、活化和存活的主要细胞因子。Mepolizumab 可用于嗜酸性肉芽肿伴多血管炎 (EGPA) 和重度嗜酸性哮喘的研究[1][2]。
存储条件:Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献:
Tim Harrison, et al. Real-world mepolizumab in the prospective severe asthma REALITI-A study: initial analysis. Eur Respir J. 2020 Oct 15;56(4):2000151.
Ian D Pavord, From DREAM to REALITI-A and beyond: Mepolizumab for the treatment of eosinophil-driven diseases. Allergy. 2022 Mar;77(3):778-797.