TAT(48-60)细胞穿膜肽 | GRKKRRQRRRPPQ

HIV-1 TAT (48-60) 是源自人免疫缺陷病毒 (HIV)-1蛋白残基48-60，可渗透细胞的多肽。它已被用于以不中断的方式将外源性大分子递送到细胞中。

HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way.

编号:179948

中文名称:细胞穿膜肽TAT(48-60)

英文名:TAT(48-60)

单字母:H2N-GRKKRRQRRRPPQ-OH

三字母:H2N-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-Gln-COOH

氨基酸个数:13

分子式:C70H131N35O16

平均分子量:1719.01

精确分子量:1718.05

等电点(PI):13.21

pH=7.0时的净电荷数:7.97

平均亲水性:2.44

疏水性值:-3.49

来源:Synthetic

纯度:95%、98%

盐体系:可选TFA、HAc、HCl或其它

生成周期:2-3周

储存条件:Powder -80°C 2 years -20°C 1 year In solvent -80°C 6 months -20°C 1 month

标签:<span class="nolink">细胞穿膜肽

参考文献：

10.1016/s0006-291x(03)01135-5Uptake of analogs of penetratin, Tat(48-60) and oligoarginine in live cells

10.1002/cphc.200600306The cell-penetrating peptide TAT(48-60) induces a non-lamellar phase in DMPC membranes

10.1074/jbc.272.25.16010A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus