《急诊每日一题》心脏移植后肌钙蛋白和脑钠肽动态变化2021年6月

Question 问题：

A patient who has had a recent cardiac transplant presents to the ED. Both troponin and BNP are elevated. Is this concerning? If so, why? 

近期做心脏移植患者到急诊就诊。肌钙蛋白和脑钠肽都有升高。这有意义吗？有与意义，为什么？

 Answer 答案：

Troponin is elevated for up to 3 months after surgery but then should normalize. BNP elevations peak within the first 2 months, then returns to normal. Troponin and BNP elevation after these periods can suggest graft rejection。

手术后肌钙蛋白持续升高，3个月后恢复正常。脑钠肽升高在头2个月内达高峰，然后恢复正常。肌钙蛋白和脑钠肽在这些时间以后升高，提示移植排斥。

参考文献：

Am J EM, epub 3/14/21