TAMRA alkyne, 5-isomer,CAS:945928-17-6
中文名称：5-羧基四甲基罗丹明-炔烃
5-四甲基罗单明炔基化物
其它名称：5-TAMRA alkyne
5-Carboxytetramethylrhodamine-Alkyne
CAS NO：945928-17-6
分子式：C28H25N3O4
分子量：467.52 g/mol
溶解性：Soluble in DMSO
含 量：95%+
外 观：固体粉末
保存方法：-20避光避湿
Ex/Em:555/575
结构式：
产品简介:
The red-fluorescent tetramethylrhodamine alkyne can be reacted with azides via a copper
catalyzed click reaction. Click chemistry describes a class of chemical reactions that use
bio-orthogonal or biologically unique moities to label and detect a molecule of interest using
a two-step procedure. The two-step reaction procedure involves a copper-catalyzed triazole
formation of an azide and an alkyne. Click reactions have several characteristics: the reaction between the detection moieties is efficient; no extreme tempe******s or solvents are required; the reaction product is stable; the components of the reaction are bioinert; and perhaps most importantly, no side reactions occur – the label and detection tags react selectively and specifically with one another. Unlike traditional chemical reactions utilizing succinimidyl esters or maleimides that target amines and sulfhydryls – functional groups that are not unique – click chemistry-labeled molecules can be applied to complex biological samples and be detected with unprecedented sensitivity due to extremely low background.
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