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活性氧Methylprotodioscin,CAS No. 54522-52-0

2023-04-23 17:31 作者:齐岳hao  | 我要投稿

产品名称:活性氧Methylprotodioscin,CAS No. 54522-52-0

产地:西安

规格:1mg 5mg 10mg

纯度:99%

用途:仅用于科研

状态:固体/粉末

储藏条件:冷藏-20℃

温馨提示:仅用于科研,不能用于人体实验!

说明:提供使用说明,核磁图谱,包装,价格,产地,制备方法,应用,稳定性,溶解度,简单合成等各种信息  

Methylprotodioscin is a steroidal saponin that has been found in A. cochinchinensis and has diverse biological activities.It suppresses mucin 5AC (MUC5AC) production induced by EGF or phorbol 12-myristate 13-acetate (PMA) in H292 cells when used at a concentration of 1 碌M.Methylprotodioscin inhibits the proliferation of HeLa cervical cancer cells (IC50 = 18.31 碌M) but has no effect on non-cancerous HEK293 cells.It also induces production of reactive oxygen species (ROS), apoptosis, and cell cycle arrest at the G2/M phase in HeLa cells. In vivo, methylprotodioscin (50 mg/kg) decreases bone loss and prevents decreases in bone mineral content and bone mineral density in a mouse model of ovariectomy-induced osteoporosis.

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编辑:XAQYBIO HAO,2023年4月23日。

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