钙离子载体A23187-BIOFOUNT

钙离子载体 A23187 离子载体(钙镁盐混合物)(Calcimycin)是一种来自沙特链霉菌的离子载体的聚醚抗生素。离子载体(钙镁盐混合物)结合并运输钙和其他二价阳离子穿过膜，并解耦氧化磷酸化，同时抑制大鼠肝线粒体的ATPase。离子载体(钙镁盐混合物)主要用作生化工具，以研究二价阳离子在各种生物系统中的作用。

溶解度:Soluble in water (Partly miscible), DMSO (1 mg/ml), and DMF (10 mg/ml).

性状 Solid power

储藏条件:储存温度2-8℃

案例：

Calcium ionophore A23187-activated PMN release dsDNA more rapidly than PMA-activated PMN. PMN (2 × 105) were incubated in the presence or absence of increasing concentrations of PMA (A) or A23197 (B) for 240 min. The presence of extracellular dsDNA was detected at the indicated times with Sytox Green. Both graphs are representative of three identical experiments and show means ± SEM of duplicate samples (C) Comparison of extracellular dsDNA levels 3 h after PMA or A23187 activation; data are means ± SEM (n = 3). AU, arbitrary units.